The occurrence of lung cancer is associated with smoking, which exposes smokers to a series of carcinogenic chemicals. CYP (cytochrome P450) usually metabolizes carcinogens to their inactive derivatives, but occasionally convert the chemicals to more potent carcinogens. In addition to the metabolism of carcinogenic compounds, CYP also participates in the activation and/or inactivation of anti-c...

Colour plays a vital role in marketing any product such as cosmetics, food additives, pharmaceutical products etc. It gives the attractiveness for product. also helps to get attention of customers. Early days synthetic dyes were used colorants these products. The carcinogenic effect and toxic made impact thirst on use natural dyes. Natural are obtained from pigments produced by microorganisms p...

Polyphenols, including anthocyanins, from various plant foods are effective in the prevention of atherosclerosis in animal and human studies. Protocatechuic acid (PCA), a major metabolite of anthocyanins, has been found to possess the anti-carcinogenic effect, whereas the in vivo effect of PCA as an anti-atherosclerotic agent remains unknown. We demonstrated herein that PCA inhibited monocyte a...

Aim In this study we attempt to indicate anti-carcinogenic influence of ether extracted metabolites of Streptomyces Levis sp. on gene expression in colon cancer. Background Colon cancer is one of the most prevalent cancers worldwide. In recent decades, researchers have been seeking the treatment for cancer. Natural products are valuable compounds with fewer side effects in comparison to chemo...

During the last decade, the burst of interest is observed to antidiabetic biguanide metformin as candidate drug for cancer chemoprevention. The analysis of the available data have shown that the efficacy of cancer preventive effect of metformin (MF) and another biguanides, buformin (BF) and phenformin (PF), has been studied in relation to total tumor incidence and to 17 target organs, in 21 var...

The binding of labeled carcinogens [3H]benzo(a)pyrene [3H]dibenz(a,/i)anthracene, and [3H]dibenz(a,c)anthracene to nuclear chromatin was examined in AKR mouse embryo cells grown in culture. The influence of unlabeled weakly and strongly carcinogenic polycyclic aromatic hydrocar bons (PAH) and the metabolic inhibitor 7,8-benzoflavone on the binding of labeled PAH to nuclear chromatin was examine...

Skin is the largest human organ, our protection against various environmental assaults and noxious agents. Accumulation of these stress events may lead to the formation of skin cancers, including both melanoma and non-melanoma skin cancers. Although modern targeted therapies have ameliorated the management of cutaneous malignancies, a safer, more affordable, and more effective strategy for chem...

Turkey is considered the gene centre of vine, and it has remained one most important trading centres viticulture grape-based foods for a long time. The grapes grown in Anatolia obtained by processing these contribute greatly to economy nation. In addition economic outcomes, traditional provide anti-carcinogenic, anti-inflammatory, antioxidant cardiovascular disease–preventing benefits when cons...