In the present study, the analgesic and anti-inflammatory activities of a new alkaloid (5′-Hydroxymethyl-1′-(1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one) (compound 1), isolated from Sida cordifolia Linn. was investigated in animal models. The analgesic activity was investigated in the acetic acid induced writhing and the radiant heat tail flick model in mice a...

To determine the pharmacological (Anti-inflammatory) potential of in-vitro cultures of Asparagus racemosus. Anti-inflammatory activity of methanolic extracts of shoot, root their calli and genetically transformed shoot culture was performed using carrageenan induced rat paw edema method. The albino rats were treated orally with two dosage (500 or 1000 mg/kg body weight of rats) of drugs, one ho...

background worldwide, the incidence of inflammatory bowel disease (ibd) is increasing. this study aims to evaluate the diagnostic value of two serological markers, atypical perinuclear anti-neutrophil cytoplasmic antibodies (atypical-p-anca) and anti-saccharomyces cerevisiae antibodies (asca), with the intent to determinetheir relationship to ulcerative colitis (uc) and crohn's disease (cd), in...

objective:the present study was designed to evaluate the antioxidant, analgesic, and anti-inflammatory activities ofthe methanolic extract of piper betle leaves (mpbl). materials and methods: mpbl was evaluated for anti-inflammatory activity using carrageenan-induced hind paw edema model. analgesic activity of mpbl was evaluated by hot plate, writhing, and formalin tests. total phenolic and fla...

Objective(s): Inflammation is an immune response toward injuries. Although inflammation is healing response, but in some condition it will lead to chronic disease such as rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, Alzheimer’s and various cancer. Indonesian cassia (Cinnamomum burmanni C. Nees & T. Ness) known to contain coumarin, is widely used for alternative medicine es...

background & aim: solanum anomalum thonn. ex schumach. (family solanaceae) is a shrub growing up to 2 metres tall. the edible fruits are gathered from the wild and consumed locally and the leaves are used locally in the treatment of various diseases. evaluation of anti-inflammatory activity of leaf extract of solanum anomalum was carried out to ascertain its uses in traditional medicine. experi...

curcumin is a hydrophobic polyphenol and major bioactive component of turmeric with known anti-inflammatory, neurogenesis, antioxidant, and anti-carcinogenic effect. curcumin antagonizes many steps in the inflammatory cascade, including inhibition of nf-κb (nuclear factor kappa-light-chain-enhancer of activated b cells), activator protein-1 transcription and inos (induced nitric oxide synthases...

in the present study, the usage pattern of anti-inflammatory drugs-steroidal and non-steroidal- in patients referred to 13 aban pharmacy in sari was evaluated. the results show a high rate of anti-inflammatory drug prescriptions, mainly by general practitioners with ibuprofen, diclofenac and mefenamic acid being the most widely used nsaids and prednisolone, dexamethasone and betamethasone being...

extracts obtained from the petals of rosa damascena (rosaceae) are used in iranian folk medicine as remedies for the treatment of some inflammatory diseases. in this study the hydroalcoholic extract and essential oil of the plant were investigated for its possible anti-inflammatory and analgesic activities. the extract was administered at the doses (p.o.) of 250, 500 and 1000?mg/kg and the dose...