Majority of people in rural areas Uganda and other malaria-endemic parts the world use medicinal plants to treat disease. This study documented used malaria around Kilembe copper mines assessed presence essential potentially toxic elements. Household surveys key informant interviews were carried out while anti-malarial sampled, prepared concentrations Fe, Mn, Zn, Co, Cu Ni determined by atomic ...

BACKGROUND The FMP2.1/AS02A candidate malaria vaccine was tested in a Phase 2 study in Mali. Based on results from the first eight months of follow-up, the vaccine appeared well-tolerated and immunogenic. It had no significant efficacy based on the primary endpoint, clinical malaria, but marginal efficacy against clinical malaria in secondary analyses, and high allele-specific efficacy. Extende...

Sickle cell disorder is the most important genetic haematological disease that affects the people of black African descent. About 2% of all babies born to Nigerian parents have sickle cell anaemia (1). The distribution of indigenous sickle cell disorder coincides with the distribution of falciparum malaria. Possession of sickle cell trait confers a natural protection against death from malaria ...

Latar Belakang: Berdasarkan data World Malaria Report tahun 2015, malaria telah menyerang 106 negara di dunia. Secara nasional angka kejadian selama 2009-2016 cenderung menurun yaitu dari 1,8 per 1.000 penduduk berisiko pada 2009 menjadi 0,84 2016. Pada 2016 Annual Parasite Incidence (API) Provinsi Riau adalah sebesar 0,05%, dengan tingkat API tertinggi terdapat Kabupaten Indragiri Hulu jumlah ...

C. odorata L. is considered to be a plant weed that scattered in various climates. As weed, this contains variety of beneficial secondary metabolites. Several studies have shown the benefits leaf extract. This study reviews metabolite content and pharmacological activities A literature search was carried out obtain related use Secondary metabolites identified are alkaloids, flavonoids, tannins,...

Antibody responses directed against the Plasmodium falciparum antigens, total extract, anti-merozoite surface protein-3 (MSP3b) and glutamate-rich protein (Glurp-R0) were studied in 42 children exposed to both Schistosoma haematobium and P. falciparum infections. The association between levels of the anti-malaria IgG subclasses and IgM with host age, sex, schistosome infection intensity and sch...

BACKGROUND We conducted a prospective study in a cohort of short-term travelers assessing the incidence rate of anti-circumsporozoite seroconversion, adherence to chemoprophylaxis, symptoms of malaria during travel, and malaria treatment abroad. METHODS Adults were recruited from the travel clinic of the Public Health Service Amsterdam. They kept a structured daily travel diary and donated bl...

Cerebral malaria (CM) and severe malarial anemia (SMA) are the most serious life-threatening clinical syndromes of Plasmodium falciparum infection in childhood. Therefore, it is important to understand the pathology underlying the development of CM and SMA as opposed to uncomplicated malaria (UM). Increased levels of hepcidin have been associated with UM, but its level and role in severe malari...