Multiple sclerosis (MS) and anti-phospholipid syndrome (APS) are chronic, immune-mediated, relapsing-remitting disorders affecting young adults. APS is characterized by thrombosis pregnancy mortality associated with antibodies. The diagnosis of may be difficult, it not uncommon for patients to misdiagnosed multiple sclerosis. In this case report, we describe a patient who was diagnosed as havin...

While it has been established that anti-phospholipid antibodies (aPL) are associated with recurrent miscarriage (RM), the importance of anti-beta2 glycoprotein 1 (GP1) IgG and anti-annexin V IgG antibodies as risk factors for RM is undefined. We have investigated the prevalence of anti-beta2 GP1 IgG and anti-annexin V IgG antibodies in 54 aPL-positive and 48 aPL-negative women with RM. The prev...

Anti-beta 2 glycoprotein 1 (anti-β2GP1) antibodies are commonly found in patients with autoimmune diseases such as the antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). Their presence is highly associated with increased risk of vascular thrombosis and/or recurrent pregnancy-related complications. Although they are a subtype of anti-phospholipid (APL) antibody, anti-β2GP1 a...

Anti-phospholipid syndrome is defined by the combination of clinical thrombosis and detection of persistent anti-phospholipid antibodies (aPL), including lupus anti-coagulant (LA). Those who do not meet full clinical criteria of overt thrombosis but still harbor circulating aPL can be characterized as "anti-phospholipid carriers." Regardless of clinical manifestations, aPL can complicate coagul...

Beta2-glycoprotein I (beta2-gpI) is a phospholipid cofactor with anticoagulant properties. A number of biological functions in the coagulation cascade have been attributed to this cofactor. Sera from patients with antiphospholipid syndrome (APS) frequently react to beta2-gpI in immunoassays. Occasionally, patients with thrombotic diathesis present anti-beta2-gpI antibodies in the absence of oth...

abstract aim: to assess anti-neuronal antibodies (na) prevalence and their correlation with neurological disorders and bowel habits in celiac disease (cd) patients. background: neurological manifestations are estimated to occur in about 10% of celiac disease patients and na to central nervous system (cns) and enteric nervous system (ens) are found in a significant proportion of them. little is ...

background : type 1 diabetes mellitus (t1dm) is an autoimmune disease characterized by selective destruction of pancreatic beta cells.   methods: the study included 80 children, 20 of them have t1dm, 40 children were selected from first degree relatives to the same child and 20 healthy children serve as control. body mass index (bmi) was calculated, random blood glucose and glycosylated hemoglo...