Ticarcillin, carbenicillin and BL-P1908, a new anti-pseudomonal semisynthetic penicillin, were subjected to several in vitro comparisons-including minimal inhibitory and lethal concentrations (MIC and MLC), effects of inoculum size, effects of buffering the media and regression analyses of MIC and disc diffusion data. Whereas ticarcillin and carbenicillin showed comparable spectra of activity, ...

objective: the present study was undertaken to evaluate the possible analgesic, neuropharmacological, anti-diarrheal, and cytotoxic activities of the ethanol extract of leaves of solanum sisymbriifolium lam. (family: solanaceae). materials and methods: the analgesic activity was measured by acetic acid-induced writhing inhibition test. the neuropharmacological activities were evaluated using ho...

One of the many functions of skin is to protect the organism against a wide range of pathogens. Antimicrobial peptides (AMPs) produced by the skin epithelium provide an effective chemical shield against microbial pathogens. However, whereas antibacterial/antifungal activities of AMPs have been extensively characterized, much less is known regarding their wound healing-modulatory properties. By ...

I share the interest shown by EVERARD et al. [1] in the use of macrolide antibiotics in cystic fibrosis (CF). Some patients with chronic Pseudomonas colonization do appear to improve when given prolonged courses of azithromycin, and the possibility that this is due to an anti-inflammatory rather than an antibacterial effect is supported by the findings of MOLINARI et al. [2] that subinhibitory ...

Kartagener syndrome is a rare, ciliopathic, autosomal recessive genetic disorder that causes a defect in the action of the cilia lining the respiratory tract and fallopian tube. Patients usually present with chronic recurrent rhinosinusitis, otitis media, pneumonia, and bronchiectasis caused by pseudomonal infection. Situs inversus can be seen in about 50% of cases. Diagnosis can be made by tes...