Introduction: Infectious diseases are one of the main causes of death worldwide. This has driven scientists to invest in extraction and identification of antimicrobial agents from natural toxins and presentation of novel antibiotics and vaccines. The aim of the current study is to investigate the antibacterial and cytotoxicity effects of the protective antigen domain 4 (PAD4) from Bacillus anth...

abstract background: the invasion of microorganisms into the bloodstream and spread to different parts of body can cause disruption the functions of vital organs and even death. the proper and prompt treatment is essential and can significantly reduce morbidity and mortality rates. this study aimed to determine the frequency and the antimicrobial susceptibility of bacteria isolated from blood c...

background and objective: nowadays, incidence of antibiotic-resistance among pathogenic bacteria has increased due to indiscriminate use of antimicrobial drugs for treatment of diseases, especially urinary tract infections. medicinal plants are also of great importance as antibacterial agents. therefore, the aim of this study was to determine the antibacterial effect of ethanolic extract of net...

introduction: the main goal of endodontic treatment is elimination of bacteria and their by-products from infected root canals. this study compared the antibacterial effect of two different sealers, ah 26 and mta fillapex, on 4 microorganisms 24, 48 and 72 h and 7 days after mixing. methods and materials: the microorganisms used in this study consisted of lactobacillus acidophilus ( atcc 4356),...

In recent years, natural biodegradable nanoparticles as stabilizers of Pickering emulsions have attracted extensive attention. this work, a emulsion composed chitosan/Arabic gum (CS/GA NPs), tea tree oil and vitamin E was formulated. Then the antibacterial, anti-inflammatory wound healing abilities were evaluated. encapsulated strengthened antibacterial activity towards Staphylococcus aureus, E...

Application of pharmacodynamic principles to antifungal drugs has provided an understanding of the relationship between drug dosing and treatment outcomes similar to that observed in antibacterial pharmacodynamics. Initial observations with triazole pharmacodynamics have correlated with clinical trial results and proved useful for validation of in vitro susceptibility breakpoints. Pharmacodynam...

White spot lesions are observed in nearly 50% of patients undergoing orthodontic treatment. Long-lasting antibacterial properties of orthodontic cements can reduce this phenomenon. The aim of this research was to compare antimicrobial activity of three commercial glass ionomer cements with three commercial zinc phosphate cements, over time, against streptococcus mutans and candida albicans. Dir...

Medicinal plants produce several antibacterial compounds. These plants are well known for their medicinal value and are widely used in community for the treatment of various diseases. In this study 5 different medicinal plants (Azadirachta indica, Ficus religiosa, Acacia nilotica, Linum usitatissimum and Rosa damascene), traditionally used in medicine, were subjected to preliminary screening fo...

Silver nanoparticles (AgNPs) have attracted great interest due to their applications in various areas. In the present study ecofriendly biosynthesis of extracellular silver nanoparticles was carried out using Candida utilis NCIM 3469. Characterization of synthesized AgNPs was done by UV-visible spectroscopy, Scanning electron microscopy and antibacterial activity. AgNPs are found spherical in s...

This study assessed the functional importance of residues located at the i(-2) position of face 4 of the tandem repeat loops of the quinolone resistance protein QnrVC7 through mutagenesis studies. The i(-2) position of face 4 on different coils required residues with different natures. Some substitutions reduced the protective activity of QnrVC7, while some of them increased it. These findings ...