conclusions silver nanoparticles have high therapeutic activity against mrsa, thus can be suggested as an alternative or adjuvant with antibiotics for mrsa treatment. further studies are required to understand the synergistic effect of ag-nps combinations and to assess the safety and efficacy of new antibiotic-ag-nps combinations. background methicillin-resistant staphylococcus aureus (mrsa) ar...

abstract background: a surgical site infection (ssi) is the most common nosocomial infection after surgery and is the third most common infection in hospitalized patients. the aim of this study was to asses minimum inhibitory concentration (mic) of the causing agents of ssi and antimicrobial susceptibility patterns. methods: this cross-sectional study was done in three referral hospitals in nor...

introduction septic cavernous sinus thrombosis (cst) is a rare condition that can result in high mortality and morbidity rates if not treated immediately. cst may be aseptic or septic. less common primary sites of infection include the tonsils, soft palate, middle ear, and orbit. reported cases of middle ear infection are very rare, and response to treatment is poor. conclusions findings of lab...

objective: aminoglycosides are highly potent, broad-spectrum antibiotics with many desirable properties for the treatment of life-threatening infections. escherichia coli (e. coli) is the most common cause of urinary tract infection (uti). antibiotic resistance has recently become prevalent. enzymatic inactivation of aminoglycosides by aminoglycoside-modifying enzymes is the main mechanism of r...

the plant kingdom constitutes a source of new chemical compounds, which may be important due to their potential uses in medicine, or their other biological properties. in this study, the effects of galbanic acid (ga), a sesquiterpene coumarin from roots of ferula szowitsiana, were investigated as a modulator of antibiotic resistance in clinical isolates of staphylococcus aureus. isolates of s. ...

objective(s): pseudomonas aeruginosa is a nosocomial pathogen resistant to most antimicrobial treatments. furthermore, it persists in adverse environments thereby forming biofilms on various surfaces. researchers have therefore focused on antibiofilm strategies using nanoparticles due to their unique physicochemical properties. superparamagnetic iron oxide nanoparticles (sionps) have recently s...

epidural abscess of the spinal column is a rare condition that can be fatal if left untreated. it promptly progresses and can cause neurologic paralysis, urinary retention or cauda equina syndrome. compromised immune system that occurs in patients with diabetes mellitus, aids, chronic renal failure, alcoholism, or cancer is a predisposing factor. it mostly occurs in adults. here we would like t...

Background: There has recently been increasing interest in the role of the human microbiome in disease. Antibiotic use is known to disrupt the intestinal microbial environment and cause acute disease, for example pseudomembranous colitis. This study aimed to investigate the hypothesis that long-term antibiotic use is associated with the development of chronic diseases, i.e., Asthma, Rheumatoid ...