Background: Goat milk kefir is a functional food with numerous health benefits, including blood sugar control, cholesterol reduction, and improved digestive health. This study aims to determine the effect of consumption on glucose levels in hyperglycaemic mice (Mus musculus) without affecting another chemistry. compared goat products other processed considered be capable controlling reducing le...

The American Diabetes Association emphasizes the importance of individualized patient care in the management of diabetes. One of the important considerations in choosing an antihyperglycemic agent is its side-effect and safety profile. This article reviews the common and clinically significant side effects of each class of agents, including ways to prevent and overcome their occurrence.

Focused structure-activity relationships of isoindoline class DPP-IV inhibitors have led to the discovery of 4b as a highly selective, potent inhibitor of DPP-IV. In vivo studies in Wistar/ST rats showed that 4b was converted into the strongly active metabolite 4l in high yield, resulting in good in vivo efficacy for antihyperglycemic activity.

Pluchea indica Less has been developed into tea bag because it contains a number of phytochemical compounds, such as lignin, terpenes, benzoids, phenylpropanoids, alkanes, saponins, catechins, alkaloids, tannins, sterols, phenolhydroquinones, and flavonoids, which have shown to several biological activities, antioxidants, anti-inflammatory, anticholesterol, antihyperglycemic. In its development...

BACKGROUND Xanthosoma violaceum is commonly observed in fallow areas of Bangladesh but almost no scientific studies exist on this plant. Rural people consume the plant on a frequent basis. The objective of this study was to scientifically analyze the antinociceptive property of methanol extract of aerial parts of the plant along with antihyperglycemic activity. METHODS Antihyperglycemic activ...

AIMS/INTRODUCTION Canagliflozin is a sodium-glucose cotransporter 2 inhibitor under development for the treatment of type 2 diabetes. Our aim was to examine its efficacy and safety as monotherapy or in combination with commonly used oral antihyperglycemic drugs in Japanese patients with type 2 diabetes. MATERIALS AND METHODS Patients on diet/exercise alone or diet/exercise plus an oral antihy...

Background: Oral contraceptive pills are commonly used in the treatment of PCOS; but, their influence on metabolic parameters is not well known. Metformin, a biguanide antihyperglycemic drug, has been shown to improve ovarian function and glucose metabolism in women with polycystic ovary syndrome (PCOS), but results concerning its effects