diet can play a vital role in cancer prevention. nowadays the scientists are looking for food materials which can potentially prevent the cancer occurrence. the purpose of this research is to examine anti-mutagenic and apoptotic effects of apigenin in human lymphoma cells. in present study human chronic lymphocytic leukemia (eheb cell line) were cultured in rpmi 1640 (sigma), supplemented with ...

cough is a common reason for seeking medical advices for children. cough is a natural defense mechanism and can frequently occur in healthy children and can be increased by urban living and polluted cities. thus, previous history, cough exacerbations factors and quality of cough are very helpful in diagnosis of pathological cough. there are different definitions for chronic cough. in this artic...

background: lactic acid bacteria (lab) isolated originally from sourdough are probably the best candidates as biopreservatives, because they are well adapted to the non-aseptic conditions in sourdough fermentation. the aim of the present study was to study antifungal properties of a dominant endogenous lab isolated from whole barley sourdough. methods: whole barley flour from a mixture of barle...

BACKGROUND The objective of this study was to evaluate the antiinflammatory, antiinfective and clinical properties of amniotic membrane (AM) when used for guided tissue regeneration (GTR) in contained interdental defects. MATERIALS AND METHODS A total of 30 subjects participated in this study. Two sites in each subject were randomly assigned into each of the following experimental groups; tes...

Mucormycosis causes mortality in at least 50% of cases despite current first-line therapies. Clinical and animal data indicate that the presence of elevated available serum iron predisposes the host to mucormycosis. Here we demonstrate that deferasirox, an iron chelator recently approved for use in humans by the US FDA, is a highly effective treatment for mucormycosis. Deferasirox effectively c...

There is a growing need for new antibiotics. Compounds that target the proton motive force (PMF), uncouplers, represent one possible class of compounds that might be developed because they are already used to treat parasitic infections, and there is interest in their use for the treatment of other diseases, such as diabetes. Here, we tested a series of compounds, most with known antiinfective a...

Proflavine (3,6-diaminoacridine) has potential for use as an antiinfective in fish, and its metabolism by rainbow trout was therefore studied. Fourteen hours after intraarterial bolus administration of 10 mg/kg of proflavine, three metabolites were found in liver and bile, and one metabolite was found in plasma using reversed-phase HPLC with UV detection at 262 nm. Treatment with hydrochloric a...

conclusions our work suggested that pomegranate (punica granatum l.) peel has potential antifungal activity against candidiasis, and it is an attractive option for the development of new management strategies for candidiasis. results maximum inhibitions were attributed to peel extract of the pomegranate cultivar against candida species. the greatest antifungal inhibition among the eight differe...

introduction: recent studies suggest that glucocorticoids modulate memory reconsolidation. moreover, cholinergic system is involved in memory reconsolidation. since glucocorticoids interact with brain cholinergic system in modulating memory processing, we investigated whether glucocorticoid influences on the reconsolidation of emotionally arousing training depend on the cholinergic system. meth...