نتایج جستجو برای: antimicrobial therapy
تعداد نتایج: 732335 فیلتر نتایج به سال:
BACKGROUND Outcomes in patients with sepsis are better if initial empirical antimicrobial use is appropriate. Several studies have shown that adherence to guidelines dictating appropriate antimicrobial use positively influences clinical outcome, shortens length of hospital stay and contributes to the containment of antibiotic resistance.Quality indicators (QIs) can be systematically developed f...
OBJECTIVES Early transition from intravenous to oral antimicrobial therapy for acute osteomyelitis in children has been suggested as a safe and effective alternative to traditional prolonged intravenous therapy via central venous catheter, but no studies have directly compared these 2 treatment modalities. We sought to compare the effectiveness of early transition from intravenous to oral antim...
The marked increase in the incidence of infections due to antibiotic-resistant gram-negative bacilli in recent years is of great concern, as patients infected by those isolates might initially receive antibiotics that are inactive against the responsible pathogens. To evaluate the effect of inappropriate initial antimicrobial therapy on survival, a total of 286 patients with antibiotic-resistan...
Despite the fact that current international guidelines suggest initiation of antimicrobial therapy within an hour of presentation with severe sepsis and septic shock, no clinical studies exist to support this recommendation (1). In reality, initiation of antimicrobial therapy for infections causing critical illness often awaits thorough clinical evaluation, resuscitative measures, initial stabi...
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Among the rickettsioses, Q fever has specific pathological and clinical features which do not allow it to be reviewed in comparison with other rickettsioses. Arthropod-borne rickettsioses comprise three distinct disease groups: spotted fever rickettsioses, typhus, and scrub typhus. Among the spotted fever rickettsioses, Rocky Mountain spotted fever (RMSF), Mediterranean spotted fever (MSF), and...
Medical researchers at Department of Infectious Diseases and Microbiology at the Stamford Hospital in Stamford, CT are studying episodes of central venous catheter-related bacteremia (CVCB) that have become common events in patients with long-term indwelling central venous catheter use. Since no standardized treatment of CVCB exists, novel approaches have been used to salvage infected catheters...
Since its introduction in the 1970s, outpatient parenteral antimicrobial therapy (OPAT) has become a standard modality for patients with many infections requiring long-term intravenous antibiotic therapy. Delivery of OPAT may occur in physicians' offices, hospital clinics, specialized infusion centers, and currently most often, patient's homes, often self-administered. Patients are selected for...
Antimicrobial agents should be administered to all patients with suspected acute cholangitis as a priority as soon as possible. Bile cultures should be performed at the earliest opportunity. The important factors which should be considered in selecting antimicrobial therapy include the agent's activity against potentially infecting bacteria, the severity of the cholangitis, the presence or abse...
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