Background: The detrimental effects of persistent stimulation with hCG were investigated in rat Leydig cells in vitro. Materials and Methods: Oxidative stress parameters such as lipid peroxidation, Reactive oxygen species(ROS), Total antioxidant capcity (TAC) and activities of antioxidant enzymes were assessed in the treated cells. Apoptosis amongest the trearted cells were detected by in situ ...

The study evaluated antioxidant status in patients with peripheral vascular disease (PVD), with and without concomitant diabetes mellitus (DM). 211 participants were divided into standardized 4 groups: patients with PVD and DM (PVD+DM+), patients with PVD without DM (PVD+DM-), patients without PVD with DM (PVD-DM+) and patients without PVD and DM (PVD-DM-). The diagnosis of PVD was established ...

background: imbalances between the oxidant-antioxidant status have been implicated in the pathogenesis of several diseases, including oral cancer. majority of oral cancer are preceded by a well-recognized group of pre-malignant lesions. however, only a small fraction of those lesions, undergo malignant transformation. hence, there is a great need to identify biological markers, which will assis...

cognitive deficits have been observed in patients with multiple sclerosis (ms) because of hippocampal insults. oxidative stress plays a key role in the pathophysiology of ms. the aim of this study was to evaluate the effects of crocus sativus l., commonly known as saffron, on learning and memory loss and the induction of oxidative stress in the hippocampus of toxic models of ms. one week after ...

The effect of alpha-tocopherol pretreatment on lipid peroxidation and antioxidant status in isoproterenol induced myocardial infarction was studied in rats. Isoproterenol administered rats showed a significant increase in lipid peroxides in serum, heart and aorta. A significant increase in serum iron level with a significant decrease in iron binding capacity was also observed. The levels of ant...

Plants activate antioxidant defense mechanisms under stress, which help maintaining the structural integrity of cell components and possibly reduces oxidative damage.  Low temperature stress leads to the production of reactive oxygen species and oxidative damage to plants. In this study, the effect of putrescine and proline on reducing the production of reactive oxygen species and increasing th...

Molybdenum (Mo) has been reported to alleviate drought stress by enhancing antioxidant defense in plants, but the underlying mechanism remains unclear. Here, we hypothesized that Mo mediates nitric oxide (NO)-induced antioxidant defense through Mo-enzymes, particularly by nitrate reductase (NR) in wheat under drought stress. The 30-day-old wheat seedlings cultivated in -Mo (0 μM Mo) and +Mo (1 ...

Drought is one of the major environmental problems in agricultural field worldwide. The present study investigated the effects of water deficit caused by exogenous application of polyethylene glycol (PEG) on cabbage (Brassica oleracea var. capitata) grown in hydroponic culture. Root length, shoot length, dry weight, and relative water content of the seedlings significantly decreased in dose dep...

The study on physicochemical properties of maltodextrin-coated cerium oxide nanoparticles was carried out. surface structure and CeO 2 were investigated. ability to perform the functions catalase peroxidase enzymes, as well inactivate hydroxyl radicals shown. Keywords: nanoparticles, oxide, catalytic activity, antioxidant activity.