نتایج جستجو برای: antipruritic

تعداد نتایج: 204  

Journal: :Acta dermato-venereologica 2012
Lindsay G Sher Jongwha Chang Isha B Patel Rajesh Balkrishnan Alan B Fleischer

The goal of this study was to perform a meta-analysis on randomized controlled trials of topical therapies compared against their vehicles, and systemic therapies compared against their placebos, and to record how these therapies changed the magnitude of pruritus associated with atopic dermatitis. A systematic search of the literature was performed using Medline, Embase, and the Cochrane Contro...

Journal: :Mediators of Inflammation 2007
Adam Reich Jacek C. Szepietowski

The pathogenesis of pruritus in psoriasis remains unclear. Many possible mediators were implicated to transmit or modulate this sensation in psoriasis, but none has been clearly proven to be a causative agent of itching. The most often discussed theory mentioned the importance of impaired innervations and neuropeptides imbalance in psoriatic skin. Other possible causes of itching might be incre...

Journal: :Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 2012
S Ständer S A Grundmann

Chronic pruritus is one of the most frequent complaints of the skin associated with a high disease burden and markedly impaired quality of life. Chronic pruritus (>6 weeks of duration) may occur in a broad variety of diseases including dermatological, systemic, neurological, psychosomatic/psychiatric and gynaecological ones and in every age group (children, adults, pregnant women, elderly patie...

Journal: :International journal of life science and pharma research 2022

Abstract: Papular urticaria is a frequent disturbing disease characterized by chronic or recurrent papules that are hypersensitive reaction to mosquito, bedbug, flea, and other insect bites. PubMed, Web of Science, Science Direct, EBSCO, Cochrane library were searched. Study articles screened title abstract using Rayyan QCRI then full-text assessment was implemented. This review investigates th...

2012
Bharti Arora Preeti Bhadauria Deepak Tripathi Alok Sharma

Sapindus emarginatus is important indigenous plant with lots of traditional importance belongs to family sapindaceae. It is commonly called as Soap nut tree which is found in most of the hilly regions of India. Each and every part of the plant is used traditionally in various ailments. Trees of genus Sapindus are cultivated in many parts of India. The secondary metabolites present in Sapindus e...

2012
Meng Huang Di Zhang Zhe-yan Sa Ying-yuan Xie Chen-li Gu Guang-hong Ding

This study investigated whether immediate acupuncture effects in the acupoint are histamine dependent. Both histamine injection and manual acupuncture stimulation increased the pain threshold (PT) after treatment compared with the model group (P < 0.01), producing an analgesic effect. After pretreatment with clemastine, an H1 receptor antagonist and an antipruritic, the increase in the animals'...

2014
Adam P. Kardon Erika Polgár Junichi Hachisuka Lindsey M. Snyder Darren Cameron Sinead Savage Xiaoyun Cai Sergei Karnup Christopher R. Fan Gregory M. Hemenway Carcha S. Bernard Erica S. Schwartz Hiroshi Nagase Christoph Schwarzer Masahiko Watanabe Takahiro Furuta Takeshi Kaneko H. Richard Koerber Andrew J. Todd Sarah E. Ross

Menthol and other counterstimuli relieve itch, resulting in an antipruritic state that persists for minutes to hours. However, the neural basis for this effect is unclear, and the underlying neuromodulatory mechanisms are unknown. Previous studies revealed that Bhlhb5(-/-) mice, which lack a specific population of spinal inhibitory interneurons (B5-I neurons), develop pathological itch. Here we...

2017
Anna Domagała Jacek Szepietowski Adam Reich

Aim To evaluate the efficacy of antihistamines in reducing pruritus in psoriasis, 61 patients were randomized to be treated for 1 week with clemastine (n = 20), levocetirizine (n = 21) or placebo (n = 20). Material and methods All patients received the same routine antipsoriatic treatment. Itch intensity was assessed with VAS and the Itch Questionnaire, and hand movements during sleep were co...

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