OBJECTIVE Cross-sectional survey research aimed at studying predictive factors of antiretroviral (ARV) drug adherence among people living with HIV/AIDS (PWHA) who attended Tawan Mai, an outpatient clinic, Taksin Hospital, Bangkok. MATERIAL AND METHOD The sample group was 230 PWHA. A random sampling technique was used to select the sample. Data were collected by interview questionnaire between...

Makoae et al. [1] stated that the development of antiretroviral (ARV) medications in the late 1990’s altered the face of HIV/AIDS, transforming it from a fatal disease into a chronic illness. According to Foundation of Professional Development (FPD) (2010) [2], since the use of the treatment, there have been records of impressive reduction in morbidity and mortality of Human Immune Deficiency V...

Elderly HIV-infected patients may present particularities on both disease evolution and morbidity, as compared to younger patients. Moreover, elderly patients are more likely to take numerous medications due to their agerelated condition. VISAGE is a French multidisciplinary study group focusing on elderly HIV-infected patients in order to evaluate and improve their therapeutic care. Our study ...

Earlier Initiation of ARV Therapy Over the past few years, several studies have been presented and published that indicate that earlier initiation of antiretroviral (ARV) therapy decreases morbidity and mortality amongst HIV+ patients [Kitahata M, et al. New Engl J Med 2009;360:1815-26; Emery S, et al. JID 2008;197:1133-1144]. A number of studies reported on specific mechanisms that could be co...

D espite the " 3 by 5 " initiative [1], which aims to treat 3 million people with antiretrovirals (ARVs) by the end of 2005, access to ARVs in resource-poor settings remains limited. Moreover, in some ARV-access programmes, free ARVs are provided only, or preferentially, to patients who are ARV naive. Treatment restricted to patients who are ARV naive was initially the case in Uganda, with the ...

BACKGROUND The Chinese government has provided health services to those infected by the human immunodeficiency virus (HIV) under the acquired immunodeficiency syndrome (AIDS) care policy since 2003. Detailed research on the actual expenditures and costs for providing care to patients with AIDS is needed for future financial planning of AIDS health care services and possible reform of HIV/AIDS-r...

Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in the updated guidelines. We aimed to determine the prevalence of INSTI-related mutations in Taiwan. Genotypic resistance assays were performed on plasma from ARV-naïve patients (N = 948), ARV-experienced but INSTI...

REMARKABLE ADVANCES IN THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) DISEASE HAVE BEEN BLUNTED BY WIDESPREAD SUBOPTIMAL ADHERENCE (IE, NONADHERENCE), WHICH HAS EMERGED AS A MAJOR BARRIER TO ACHIEVING THE PRIMARY GOAL OF ANTIRETROVIRAL (ARV) THERAPY: suppression of HIV viral load. Nonsuppressed HIV viral load is associated with drug resistance, increased morbidity and mortality, and a high...

BACKGROUND In the Asia-Pacific region many countries have adopted the WHO's public health approach to HIV care and treatment. We performed exploratory analyses of the factors associated with first major modification to first-line combination antiretroviral therapy (ART) in resource-rich and resource-limited countries in the region. METHODS We selected treatment naive HIV-positive adults from ...

BACKGROUND Little is known about immunovirological treatment outcomes and adherence in HIV/AIDS patients on antiretroviral therapy (ART) treated using a simplified management approach in rural areas of developing countries, or about the main factors influencing those outcomes in clinical practice. METHODS Cross-sectional immunovirological, pharmacological, and adherence outcomes were evaluate...