BACKGROUND AND OBJECTIVES Currently there is no agreement regarding which one is the most adequate anesthetic technique for the treatment of retinopathy of prematurity. Peribulbar block may reduce the incidence of oculocardiac reflex and postoperative apnea. The goal of this study was to report the outcomes of peribulbar block, when combined with general anesthesia, for the laser treatment for ...

BACKGROUND Doxapram has been advocated as a treatment for persistent apnea of prematurity (AOP). OBJECTIVE To evaluate the effect of doxapram on long-term neurodevelopmental outcome in preterm infants as its safety still needs to be established. METHODS From a retrospective cohort of preterm infants with a gestational age (GA) <30 weeks and/or a birth weight <1,250 g, born between 2000 and ...

Activation of the laryngeal mucosa results in apnea that is mediated through, and can be elicited via electrical stimulation of, the superior laryngeal nerve (SLN). This potent inhibitory reflex has been suggested to play a role in the pathogenesis of apnea of prematurity and sudden infant death syndrome, and it is attenuated by theophylline and blockade of GABA(A) receptors. However, the inter...

OBJECTIVES To study the pharmacokinetics of theophylline and its correlations to pharmacodynamic effects in apnea of prematurity in small for gestational age babies. DESIGN Prospective case control study. SETTING Level III Neonatal Intensive Care Unit. SUBJECTS Ten small for gestational age (SGA) babies and 10 gestation matched appropriate for gestational age (AGA) babies with recurrent a...

BACKGROUND Apnea of Prematurity (AOP) is common, affecting the majority of infants born at <34 weeks gestational age. Apnea and periodic breathing are accompanied by intermittent hypoxia (IH). Animal and human studies demonstrate that IH exposure contributes to multiple pathologies, including retinopathy of prematurity (ROP), injury to sympathetic ganglia regulating cardiovascular action, impai...

purpose: to determine the incidence of retinopathy of prematurity (rop) and to evaluate the possible neonatal risk factors for rop among premature infants referred to farabi eye hospital during 2000-2002. methods: newborn infants with gestational age (ga) £ 37 wk or birth weight (bw) £ 2500 g were included. the first eye examination was performed 4-9 weeks after birth. data on possible risk fac...

The usefulness of caffeine to ameliorate the situationmay point to the apnea of central origin and the patient’s prematurity. The prognosis of holoprosencephaly is very poor, with only 50% of patients surviving by 4 to 5 months of age, and only 20% of patients surviving beyond 12 months of age. Treatment is usually supportive. Ventriculoperitoneal shunt for hydrocephalus, fundoplication, or gas...