نتایج جستجو برای: apolipoproteins e

تعداد نتایج: 1023956  

Journal: :Diseases 2023

Glycated hemoglobin (HbA1c) is used to assess glycemic control in Type 1 diabetes (DM1) patients. Apolipoproteins play an essential role DM1 pathophysiology and may be associated with complications HbA1c. This cross-sectional observational study of 81 children adolescents both sexes diagnosed investigated the relationship between body fat distribution lean mass HbA1C apolipoprotein values, anal...

Journal: :The Journal of biological chemistry 1984
A Jonas S A Sweeny P N Herbert

Micellar, discoidal complexes of human apolipoproteins A-I, A-II, C-I, C-II, C-III-1, and C-III-2 with egg phosphatidylcholine (egg-PC) and cholesterol were prepared by the cholate dialysis method. The complexes, isolated by gel filtration, had similar lipid and protein contents by weight, on the average: 1.77:0.083:1.0, egg-PC/cholesterol/apolipoprotein (w/w). The diameters of the discs, visua...

2001
Patrick J. Babin

The apolipoproteins of trout plasma lipoproteins have been characterized by sodium dodecyl sulfateglycerol polyacrylamide gel electrophoresis. The high density lipoproteins (HDL) (1.085 < d < 1.21 g/ml) contain four apolipoproteins, two major species with M, 25,000 (apoA-I-like) and M, 13,000 (apoA-11-like) and two minor species (M, 55,000 and 40,500). The very low density (d < 1.015 g/ml) and ...

Journal: :Thrombosis and haemostasis 2012
Inge M van Schouwenburg Bakhtawar K Mahmoodi Ron T Gansevoort Friso L H Muntinghe Robin P F Dullaart Hanneke C Kluin-Nelemans Nic J G M Veeger Karina Meijer

Studies on the association between lipid profile and venous thromboembolism (VTE) are inconsistent. This could be caused by classical lipoproteins being inferior to apolipoproteins as markers for VTE risk. Therefore, we examined whether apolipoproteins are more strongly related to VTE than lipoproteins. For this analysis we used the PREVEND prospective community based observational cohort study...

2005
Murray W. Huff W. Carl Breckenridge Bernard M. Wolfe

The C apolipoproteins are normally transferred to high density llpoprotelns (HDL) after lipolysis of very low density llpoproteln (VLDL) trlglycerlde. In previous studies, a loss of plasma C apolipoproteins was documented after heparin-induced lipolysis In hypertriglyceridemic subjects. The present studies were designed to determine If this decline In plasma C apolipoproteins was due to their c...

2014
Takasuke Fukuhara Masami Wada Shota Nakamura Chikako Ono Mai Shiokawa Satomi Yamamoto Takashi Motomura Toru Okamoto Daisuke Okuzaki Masahiro Yamamoto Izumu Saito Takaji Wakita Kazuhiko Koike Yoshiharu Matsuura

Apolipoprotein B (ApoB) and ApoE have been shown to participate in the particle formation and the tissue tropism of hepatitis C virus (HCV), but their precise roles remain uncertain. Here we show that amphipathic α-helices in the apolipoproteins participate in the HCV particle formation by using zinc finger nucleases-mediated apolipoprotein B (ApoB) and/or ApoE gene knockout Huh7 cells. Althoug...

2017
Takasuke Fukuhara Tomokazu Tamura Chikako Ono Mai Shiokawa Hiroyuki Mori Kentaro Uemura Satomi Yamamoto Takeshi Kurihara Toru Okamoto Ryosuke Suzuki Kentaro Yoshii Takeshi Kurosu Manabu Igarashi Hiroshi Aoki Yoshihiro Sakoda Yoshiharu Matsuura

Amphipathic α-helices of exchangeable apolipoproteins have shown to play crucial roles in the formation of infectious hepatitis C virus (HCV) particles through the interaction with viral particles. Among the Flaviviridae members, pestivirus and flavivirus possess a viral structural protein Erns or a non-structural protein 1 (NS1) as secretory glycoproteins, respectively, while Hepacivirus inclu...

2002
Denis Hochstrasser Francisco Barja Alex F. Muller

The protein heterogeneity of fractions isolated by immunoanity chromatography on anti-apolipoprotein A-I and anti-apolipoprotein A-I1 affinity columns was analyzed by high resolution two-dimensional gel electrophoresis. The two-dimensional gel electrophoresis profiles of the fractions were analyzed and automatically compared by the computer system MELANIE. Fractions containing apolipoproteins A...

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