Este trabalho aborda a questão da apre(e)ndizagem escrita pelo sujeito-criança que chega à escola e é convidado pelo(a) professor(a) marcar o papel. Partindo compreensão de como uma experiência singular está prova do inconsciente, artigo estruturado em três seções: i) “Da relação pais-bebê pais-criança-escola”, buscamos elucidar caminho constituição sujeito ao chão já marcado por ser objeto des...

Duringblastocyst formation, inner cellmass (ICM) cells differentiate into either epiblast (Epi) or primitive endoderm (PrE) cells, labeled by Nanog and Gata6, respectively, and organized in a salt-and-pepper pattern. Previous work in the mouse has shown that, in absence of Nanog, all ICMcells adopt aPrE identity.Moreover, the activationor the blockade of the Fgf/RTK pathway biases cell fate spe...

PURPOSE To study the role of long non-coding RNA (lncRNA) MALAT1 in transforming growth factor beta 1 (TGF-β1)-induced epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells. METHODS ARPE-19 cells were cultured and exposed to TGF-β1. The EMT of APRE-19 cells is confirmed by morphological change, as well as the increased expression of alpha-smooth muscle actin (αSMA)...

In this paper, we revisit security notions for dedicated-key hash functions, considering two essential theoretical aspects; namely, formal definitions for security notions, and the relationships among them. Our contribution is twofold. First, we provide a new set of enhanced security notions for dedicated-key hash functions. The provision of this set of enhanced properties has been motivated by...

We have analyzed the regulons of the Bacillus subtilis two-component regulators DegU, ComA and PhoP by using whole genome DNA microarrays. For these experiments we took the strategy that the response regulator genes were cloned downstream of an isopropyl-beta-D-thiogalactopyranoside-inducible promoter on a multicopy plasmid and expressed in disruptants of the cognate sensor kinase genes, degS, ...

The most sophisticated survival strategy Bacillus subtilis employs is the differentiation of a subpopulation of cells into highly resistant endospores. To examine the expression patterns of non-sporulating cells within heterogeneous populations, we used buoyant density centrifugation to separate vegetative cells from endospore-containing cells and compared the transcriptome profiles of both sub...

many factors including genetic, environmental, and acquired are involved in breast cancer development across various societies. among all of these factors in families with a history of breast cancer throughout several generations, genetics, like predisposing genes to develop this disease, should be considered more. early detection of mutation carriers in these genes, in turn, can play an import...