With the escalating prevalence of malaria in recent years, artemisinin demand has placed considerable stress on its production worldwide. At present, the relative low-yield of artemisinin (0.01-1.1 %) in the source plant (Artemisia annua L. plant) has imposed a serious limitation in commercializing the drug. Amorpha-4, 11-diene synthase (ADS) has been reported a key enzyme in enhancing the arte...

The aim of this study was preparation of a standard extract from the leaves of Artemisia absinthium in order to add into a suspention formula as a laxative agent for use in animal husbandry. As approved by the commission E, the Artemisia absinthium preparations are used internally for loss of appetite, dyspeptic, liver, and gallbladder complaints. A. absinthium is commonly used in food industry...

BACKGROUND The aim of this study was to investigate the 'acaricidal effect' of Zataria multiflora and Artemisia annua essential oils on Rhipicephalus (Boophilus) annulatus. METHODS This study was carried out in 2009 in the Laboratory of Parasitology of the Faculty of Veterinary Medicine of Shahrekord University, west central Iran. Six dilutions (5, 10, 20, 40, 60 and 80 µL/cm(3)) of both esse...

Artemisinin (quinghaosu) is a natural compound, isolated from Artemisia annua L. (Compositae), of current interest in treatment of drug-resistant malaria. Aim of the current study was to hit upon novel artemisinin sources as alternative to A. annua. Therefore, ten species of the genus Artemisia (A. santonicum L., A. taurica Willd., A. spicigera K. Koch, A. herba-alba Asso, A. haussknechtii Bois...

Four new compounds obtained from cultured cells of Artemisia annua were reported. Products were detected by HPLC-ELSD/GC-MS and isolated by chromatographic methods. The structures of four new compounds, namely 6-hydroxy arteannuin I (1), 1-hydroxy arteannuin I (2), 2-hydroxy arteannuin J (3), and 14-hydroxy arteannuin J (4), were elucidated using their physico-chemical properties by NMR and MS ...

In our ongoing investigation into Artemisia annua for the treatment of malaria, we decided to study the possibility that synergism might enhance the efficacy of artemisinin. Our main objective was to test tea infusions and nonpolar extracts prepared from different A. annua varieties against Plasmodium falciparum in vitro in order to determine if synergism will increase the effectiveness of arte...

In the study we focus on determining the contents of artemisinin in Artemisia annua L. from different geographical origins of southwest district of China. The artemisinin contents of eleven samples are measured by the high performance liquid chromatography (HPLC). As a result, Artemisinin exists in different parts of A. annua plant and the content is as follow: inflorescences > leaves > stems. ...