To solve the water pollution problem caused by methylene blue (MB), areca residue biochar (ARB) was prepared pyrolysis at 600 °C, and modified (M-ARB) obtained modifying ARB with 1.5 mol/L NaOH, they were utilized to adsorb eliminate MB from water. The structural characteristics of M-ARB examined, main influencing factors adsorption mechanism process investigated. outcomes demonstrated an incre...

AIMS/INTRODUCTION We aimed to evaluate the potential benefits and adverse effects of adding a mineralocorticoid receptor antagonist (MRA) to angiotensin-converting enzyme inhibitors (ACEI) and/or angiotensin receptor blockers (ARB), as standard treatment in patients with diabetic nephropathy. MATERIALS AND METHODS We scanned the Embase, PubMed and Cochrane Central Register of Controlled Trial...

This research investigated the regulation of aromatase and androgen receptor gene expression in the brain-pituitary-gonad (BPG) axis of male and female European eels (Anguilla anguilla) during induced sexual maturation. Complete A. anguilla aromatase (aa-cyp19a1) and partial androgen receptor α and β (aa-ara and aa-arb) sequences were isolated, and qPCR assays were validated and used for quanti...

Objectives The combined neprilysin/rennin-angiotensin system inhibitor sacubitril/valsartan (LCZ696) has shown its superiority over ACEI/ARB therapy. In view of the existing concern of its adverse effects, we aimed to provide evidence of the safety of the new drug. Results A total of 6 randomized trials with 11,821 subjects were included in this analysis. No significant differences were found...

BACKGROUND AND OBJECTIVES It is widely known that angiotensin-II receptor blockers (ARBs) have reverse remodeling effects in atrium. Although atrial fibrillation is frequent in ischemic heart failure clinically, experiments to demonstrate ARB's effects on atrial remodeling in a heart failure model are rare. MATERIALS AND METHODS A heart failure model and a sham-operated group were formed in 2...

AIMS In accordance with current guidelines, patients discharged after acute myocardial infarction (AMI) are usually prescribed agents acting on the renin-angiotensin system (ACE-I/ARB). However, adherence to prescribing medications is a recognized problem and most studies demonstrating the value of adherence were limited by their non-randomized design and by 'healthy-adherer' bias. Herein we so...

Background As the observation periods of large-scale clinical studies are relatively short, the pharmacoeconomical advantage of different first-line drugs in lifetime hypertension treatment is unknown. Methods Based on the results of large-scale clinical studies, phase III clinical trials and epidemiological data, we constructed a Markov model for patients with moderate essential hypertension t...

OBJECTIVES We tested the hypothesis that angiotensin II type 1 receptor blocker (ARB) may improve beta-adrenergic receptor (AR) coupling in heart failure (HF) after myocardial infarction (MI). BACKGROUND Beta-AR desensitization is one of the mechanisms underlying the transition from compensated to decompensated HF. Beta-adrenergic receptor kinase-1 (ARK1), which can be induced by protein kina...

techniques of severe plastic deformation have been successfully used for the production of novel metallic microstructures. among different types of these techniques, accumulative roll bonding (arb) has been extensively used to produce multi-layered composites. in the present study, a new manufacturing process for cu/ni- 1vol% fe3o4 composites was developed by using copper and nickel sheets toge...