Structure-activity relationship (SAR) is one of the foundational principles of biomolecular activity and states that similar molecules have similar biological activity. This work is focused on the utilization of enzymatic reactions in order to augment ligands with small apolar substituents. These modified molecules will then be employed for establishing the SAR of a ligand series. For this purp...

A discrete t-norm is a binary operation on a finite subset of the real unit interval fulfilling the same algebraic conditions as t-norms. We show that any left-continuous t-norm can, in a natural sense, be approximated by a discrete t-norm with an arbitrary precision.

The spheroidal wave functions, which are the solutions to the Helmholtz equation in spheroidal coordinates, are notoriously difficult to compute. Because of this, practically no programming language comes equipped with the means to compute them. This makes problems that require their use hard to tackle. We have developed computational software for calculating these special functions. Our softwa...

This paper presents a branching process approach to determine the main performance measures of a variety of conflict resolution algorithms known as tree algorithms with free access. In particular we present an efficient approach to calculate the mean delay, number of transmission attempts, collision resolution interval length and energy usage with arbitrary precision. 2013 Elsevier B.V. All rig...

I consider an arbitrary-precision computation of the incomplete Gamma function from the Legendre continued fraction. Using the method of generating functions, I compute the convergence rate of the continued fraction and find a direct estimate of the necessary number of terms. This allows to compare the performance of the continued fraction and of the power series methods. As an application, I s...

Recent electroweak precision measurements from ee and pp colliders are presented. Some emphasis is placed on the recent developments in the heavy flavor sector. The measurements are compared to predictions from the Standard Model of electroweak interactions. All results are found to be consistent with the Standard Model. The indirect constraint on the top quark mass from all measurements is in ...

We are investigating the design of tools to support everyday scientific creativity in distributed collaboration. Based on an exegesis of theoretical and empirical literature on creativity and group dynamics, we present and justify three requirements for supporting creativity: support for divergent and convergent thinking, development of shared objectives, and reflexivity. We elaborate on these ...