Aromatase inhibitors (AIs) are standard of care in the adjuvant setting of postmenopausal women with hormone receptor positive breast cancer. Despite their beneficial effects on survival outcomes in breast cancer, AIs-induced arthralgia (AIA) is a common side effect which may lead to drug discontinuation and decreased AIs adherence among patients. So far, the exact pathophysiology of AIA is sti...

sand fly fever (sf) is an arthropod-borne viral disease, also known as “phlebotomus fever”, ‘’mosquito fever’’, three-day fever or “papatacci fever”. it is transmitted by phlebotomus papatasi , starts with acute onset of high fever, and lasts for three days. we present first cases in a different district of turkey with the clinical findings of fever, myalgia-arthralgia, headache, gastrointestin...

ObjectivesTo investigate risk factors for persistent arthralgia in patients with chikungunya, and describe its impact on daily activities.MethodsFrom September 2014 to July 2016, a surveillance study enrolled acute febrile illness Salvador, Brazil, detected those chikungunya virus infection using IgM enzyme-linked immunosorbent assay or reverse transcriptase polymerase chain reaction. Telephone...

Chikungunya virus (CHIKV) is a mosquito-transmitted pathogen that causes chikungunya disease (CHIK); the characterized by fever, muscle ache, rash, and arthralgia. This arthralgia can be debilitating long-lasting, seriously impacting quality of life for years. Currently, there no specific therapy available CHIKV infection. We have developed despeciated equine polyclonal antibody (CHIKV-EIG) tre...

Extrahepatic manifestations are frequently encountered among patients with chronic hepatitis C virus (HCV) infection. Many of these manifestations are autoimmune disorders, with added mortality and morbidity due to involvement of multiple organ systems. Symptoms of HCV infection and rheumatic diseases may be similar and include arthralgia, myalgia, arthritis, and vasculitis. Also, serologic abn...