نتایج جستجو برای: arx model structure
تعداد نتایج: 3409268 فیلتر نتایج به سال:
The specification and differentiation of pancreatic endocrine cell populations (α-, β-, δ, PP- and ε-cells) is orchestrated by a combination of transcriptional regulators. In the pancreas, Aristaless-related homeobox gene (Arx) is expressed first in the endocrine progenitors and then restricted to glucagon-producing α-cells. While the functional requirement of Arx in early α-cell specification ...
The Aristaless-related homeobox (ARX) gene is implicated in intellectual disability with the most frequent pathogenic mutations leading to expansions of the first two polyalanine tracts. Here, we describe analysis of the ARX gene outlining the approaches in the Australian and Portuguese setting, using an integrated clinical and molecular strategy. We report variants in the ARX gene detected in ...
The time series analysis approach for damage detection employed by Los Alamos National Laboratory (LANL) is modified and applied to the benchmark building designed by ASCE task group for damage detection and localization. A two-tier prediction model, using the auto-regressive (AR) and the autoregressive model with exogenous inputs (ARX) is used for obtaining the damage sensitive feature. The da...
Genes encoding homeodomain-containing proteins potentially involved in endocrine pancreas development were isolated by combined in silico and nested-PCR approaches. One such transcription factor, Arx, exhibits Ngn3-dependent expression throughout endocrine pancreas development in alpha, beta-precursor, and delta cells. We have used gene targeting in mouse embryonic stem cells to generate Arx lo...
Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome.
Infantile spasms are a catastrophic form of pediatric epilepsy with inadequate treatment. In patients, mutation of ARX, a transcription factor selectively expressed in neuronal precursors and adult inhibitory interneurons, impairs cell migration and causes a major inherited subtype of the disease X-linked infantile spasms syndrome. Using an animal model, the Arx((GCG)10+7) mouse, we determined ...
Mutations in the Aristaless related homeobox (ARX) gene are associated with a broad spectrum of disorders, including nonsyndromic X-linked mental retardation, sometimes associated with epilepsy, as well as syndromic forms with brain abnormalities and abnormal genitalia. Furthermore, ARX mutations have been described in a few patients with autism or autistic features. In this study, we screened ...
A method for offline system identification to model the attitude dynamics of an unmanned helicopter using neural network techniques has been developed. The processed test data obtained from various test flights were used to train a neural network ARX (autoregressive structure with extra inputs) using Levenberg-Marquardt computation. An optimised network structure was obtained using a combinatio...
In this paper, the idea of fertilizing fuzzy neural networks with wavelets is borrowed and enhanced to introduce a novel neural network named Auto Regressive eXogenous Local Model (ARXLM) network. The enhanced network has a set of notable features compared with previous published fertilized networks. These features can be summarized as follows. First, the proposed network has a simple and plast...
The variable structure control theory based on estimated model is proposed in this paper. The ARX theory is applied to figure out the parameters of estimated model of unknown system on-line. According to the estimated, the variable structure control can be developed and implemented to this unknown system like known system. The equivalent controller of variable structure control rule will work t...
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