نتایج جستجو برای: aryl aldehyde

تعداد نتایج: 28339  

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد شاهرود - دانشکده شیمی 1391

اسانس دو گیاه ajuga chamaecistus و mrsdenia erecta با استفاده از دستگاه کلونجر استحصال گردید و اثر آنتی اکسیدان آنها برسی شده است که اثر آنتی اکسیدانی a.chamaecistus بیشتر از m.erecta بوده است. ترکیبات اصلی موجود در این دو گیاه شامل موارد زیر است: n compound name ajuga % 1 ?-pinene ?/?? 2 n-decane ?/?? 3 limonene ??/? 4 ?-bour bonene ??/?? 5 ?-cubebene ?/? 6 trans-?-farnesene ?/? ...

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2015
Yating Cheng Un-Ho Jin Clint D Allred Arul Jayaraman Robert S Chapkin Stephen Safe

The tryptophan microbiota metabolites indole-3-acetate, indole-3-aldehyde, indole, and tryptamine are aryl hydrocarbon receptor (AhR) ligands, and in this study we investigated their AhR agonist and antagonist activities in nontransformed young adult mouse colonocyte (YAMC) cells. Using Cyp1a1 mRNA as an Ah-responsive end point, we observed that the tryptophan metabolites were weak AhR agonists...

2010
S. Iglauer Y. Wu P. Shuler

We studied the influence of molecular structural elements of alkyl polyglycoside (APG) surfactants on the interfacial tension (IFT) in aqueous formulations against n-octane. This included the analysis of alkyl and aryl chain length, type and number of sugar-ring head, anomers, addition of cosolvents and effect of salt addition. We found that longer alkyl or aryl chains lead to lower IFT, consis...

2012
Ravindra Kumar Abha Shukla

A series of Azetidinone; 3-chloro-1-{4-[8-(2hydroxy-4-methylphenyl)-6,10-dimethyl-4,12-diphenyl2,4,5,11,12-pentaazatricyclo[7.3.0.0 3,7 ]dodeca-1(9), 3(7), 5,10tetraen-2-yl]phenyl}-4-aryl azetidin-2-one (3a-e) and thiazolidinones; 3-{4-[8-(2-hydroxy-4-methylphenyl)-6,10dimethyl-4,12-diphenyl-2,4,5,11,12pentaazatricyclo[7.3.0.0 3,7 ]dodeca-1(9), 3(7), 5,10-tetraen-2yl]phenyl}-2-aryl-1,3-thiazoli...

2012

A mild method for the cross-coupling of arylboronic acids with CF3I via the merger of photoredox (to generate CF3 radical) and Cu catalysis (to generate reactive Cu−aryl species) was developed by Professor Sanford and her co-worker of University of Michigan (J. Am. Chem. Soc. 2012, 134, 9034− 9037). Potassium carbonate was found a base of choice for the promotion of transmetalation in DMF solve...

2015
Jalal Hasan Mohammed

In this study the chemistry of chalcones has generated intensive scientific interest due to their biological and industrial applications. Chalcones are natural biocides and are well known intermediates in the synthesis of heterocyclic compounds exhibiting various biological activities. Chalcones and their derivatives possess some interesting biological properties such as antibacterial, antifung...

2015
Manoj Kumar Lokesh Kumar Kumawat Vinod Kumar Gupta Anuj Sharma

Furans are an important class of compounds and exhibit a diverse range of activities and properties. As such, improved synthetic access to furans is an important research goal. In the present report, a solvent- and catalyst-free reaction between 5,5-dimethyl-1,3-cyclohexanedione (dimedone), an aryl aldehyde and an isocyanide under microwave irradiation is presented. This method is significantly...

Journal: :Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2003
Katsumi Nishimura Kiyoshi Tomioka

As a part of our studies aimed at asymmetric catalytic reactions by using an external chiral ligand, we have developed a catalytic asymmetric addition reaction of an arylthiol to alpha,beta-unsaturated esters under the control of an external chiral ligand. The characteristic of our technology is a double activation of a thiol by lithiation and chelate formation with a chiral tridentate amino di...

2014
Mario Sanches Nicole M. Duffy Manisha Talukdar Nero Thevakumaran David Chiovitti Marella D. Canny Kenneth Lee Igor Kurinov David Uehling Rima Al-awar Gennadiy Poda Michael Prakesch Brian Wilson Victor Tam Colleen Schweitzer Andras Toro Julie L. Lucas Danka Vuga Lynn Lehmann Daniel Durocher Qingping Zeng John B. Patterson Frank Sicheri

Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA substrates to re-establish ER homeostasis. Aromatic ring systems containing hydroxy-aldehyde moieties, termed hydroxy-aryl-aldehydes (HAA), selectively inhibit IRE1α RNase an...

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