1. Ascorbic acid was absorbed across the mucosa of the human mouth. 2. Omission of sodium ions from the medium decreased the absorption of ascorbic acid. 3. The presence of D-glucose, or 3-O-methyl-D-glucose, increased the absorption of ascorbic acid but D-fructose had little effect and D-mannitol had no effect. 4. Calcium ions also increased ascorbic acid absorption probably by a secondary ef...

1. The effect ofdietary molybdenum on the growth rate and also on ascorbic acid metabolism in rats was studied. An excess of dietary molybdenum resulted in growth retardation and loss of weight. Tolerance to molybdenum was affected by the nature ofthe molybdenum salt administered. 2. Molybdenum ingestion altered certain aspects of ascorbic acid metabolism in rats. The conversion ofD-glucuronola...

BACKGROUND Ascorbic acid reduced the severity of neuropathy in transgenic mice overexpressing peripheral myelin protein 22 (PMP22), a model of Charcot-Marie-Tooth disease type 1A (CMT1A) associated with the PMP22 duplication. However, in three 1-year trials, ascorbic acid had no benefit in human beings. We did a multicentre 2-year trial to test the efficacy and tolerability of ascorbic acid in ...

Ascorbic acid is frequently administered intravenously by alternative health practitioners and, occasionally, by mainstream physicians. Intravenous administration can greatly increase the amount of ascorbic acid that reaches the circulation, potentially increasing the risk of oxalate crystallization in the urinary space. To investigate this possibility, we developed gas chromatography mass spec...

Although it is generally realized that environmental factors may influence the nutritive value of fruits and vegetables, there has not been a great deal of research reported to show the extent to which climatic variants may exert their effect. The work reported in this paper is concerned with the relationship between sunlight and the ascorbic acid content of strawberries. Reports in the literat...

Cadmium (Cd) is a testicular toxicant which induces endoplasmic reticulum (ER) stress and germ cell apoptosis in testes. This study investigated the effects of ascorbic acid on Cd-evoked ER stress and germ cell apoptosis in testes. Male mice were intraperitoneally injected with CdCl(2) (2.0 mg/kg). As expected, a single dose of Cd induced testicular germ cell apoptosis. Interestingly, Cd-trigge...

A simple and sensitive flow injection fluorometric method for the determination of ascorbic acid is described. Perylenebisimide-linked nitroxide (PBILN) is used as a fluorescent reagent, which permits the selective determination of ascorbic acid. The fluorescence of the perylenebisimide moiety in PBILN is quenched by the nitroxide moiety, which is linked to the perylenebisimide. When a stream o...

Wheat (Triticum aestivum L.) is widely cultivated in the Mediterranean zone where plantsgenerally suffer from water stress during heading and reproductive stages. This research wascarried out at the experimental farm of the faculty of agriculture, Kafrelsheikh University usingtwo water treatments (water stress and well-watered), four N levels (0, 80, 160 and 240 kg ha-1)and two ascorbic acid le...

this investigation determined that vitamin c intake of c.w. was higher than o.p. , s. c. and c. statistically, there was a significant difference between c.w. and c. blood ascorbic acid levels of o.p. and s.c. were lower than c.w. and c. , a significant difference was observed. urinary vitamin c in all groups was lower than controls and this indicates that even though vitamin c intake was high,...