Various investigators have reported changes in the concentration of the free amino acids in blood plasma and tissues of guinea-pigs in acute vitamin C deficiency. Christensen & Lynch (1948) found in guinea-pigs deficient in ascorbic acid a large decrease in the glycine and glutamine contents of skeletal muscle and in the glutamine content of the liver. Levels of amino acids other than glycine a...

introduction: the influence of ascorbic acid on the nicotine-induced conditioned place preference (cpp) and behavioral sensitization was investigated in the present study. methods: in a pilot study, place conditioning and locomotor activity were investigated after nicotine (0.25, 0.5, 0.75, 1, 1.5 and 2 mg/kg) or ascorbic acid (1, 10, 100 and 1000 mg/kg) administration. different doses of ascor...

the effects of thiamine, ascorbic acid ami their combination an workers who are continuously exposal to lead has been investigated. in this study 60 persons in a battery industry was selected and divided into four equal groups. group i received placebo, group ii thiamine (300 mg), group iii ascorbic acid (250 mg) anil group iv thiamine (300 mg) plus ascorbic acid (250 mg) three times a day (ora...

after maxillary expansion, a long period of retention is necessary to prevent early relapse. therefore, it is beneficial to accelerate bone formation in the expanding midpalatal suture to reduce relapse. this study was designed to evaluate the effect of dietary vitamin c on osteogenesis of rat midpalatal suture during expansion.fifty-four male wistar rats were randomly divided into three groups...

1. The effect of ascorbic acid deficiency on glycosaminoglycans of granulation tissue and cartilage of guinea pigs was investigated by determination of the changes in the glucosamine and galactosamine contents 12 days after tendonectomy. 2. In normal granulation tissue, the glucosamine and galactosamine contents rose to a peak at 5 and 10 days respectively, whereas the hydroxyproline and prolin...

In this study, a new reaction system for quantitative determination of ascorbic acid was introduced. The developed method is based on inhibitory effect of ascorbic acid on the Orange G-bromate system. The change in absorbance was followed spectrophotometrically at 478 nm. The dependence of sensitivity on the reaction variables including reagents concentration, temperature and time was investiga...

Background & Aims: Stroke is the third leading cause of death. Oxidative stress has a principal role in the complications of stroke. Due to this fact and the antioxidant effects of ascorbic acid, this study was designed to evaluate the effect of ascorbic acid on reduction of stroke complications in a permanent model of middle cerebral artery (MCA) occlusion in male rats. Methods: In this experi...

since the waste of agricultural and horticultural products is high, appropriate methods should be used to produce products with high quality and shelf life for export. in iran a great part of fruits and vegetables are dried conventionally and farmer use so2 gas for preservation and color stability of dried apricots ,but this gas is allergic and carcinogenic and effort to find suitable substitut...