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By introgressing Neurospora crassa translocations into N. tetrasperma, we constructed heterokaryons bearing haploid nuclei of opposite mating types, and either the translocation and normal sequence chromosomes (i.e., [T + N]) or a duplication and its complementary deficiency (i.e., [Dp + Df]). The [T + N] heterokaryons result from alternate segregation of homologous centromeres, whereas adjacen...

The aim of this quality controlling study was to determine the accuracy of liquid-based cytology (LBC) with the Turbitec cytocentrifuge technique. Cervical smears of 632 women, who were referred to our CIN outpatient department, after at least two smears with ASCUS or higher were evaluated and compared with the histological outcome. In 592 cases the smears revealed abnormalities of squamous epi...

Yeasts in the lager brewing group are closely related and consequently do not exhibit significant genetic variability. Here, an artificial Saccharomyces cerevisiae × eubayanus tetraploid interspecies hybrid was created by rare mating, its ability to sporulate produce viable gametes exploited generate phenotypic diversity. Four spore clones obtained from a single ascus were isolated, their brewi...

A discomycete collected in western Sichuan, China, is morphologically intermediate between Cudonia and Spathularia. The fungus has a bright yellow capitate ascigerous head, a white, ridged stalk, and a well-developed membrane covering the whole ascoma. The asci, ascospores, and paraphyses are similar to those of Cudonia and Spathularia. Based on morphology and DNA sequence analysis, a new speci...

Low-grade cytological abnormalities of the cervix can be challenging to manage; while most will clear without intervention, between 10% and 20% could harbour high-grade lesions. Furthermore, low-grade abnormalities represent the largest category of abnormal results. In Scotland, of the 409 000 cervical screening tests that were performed in 2011–2012, 90.9% had a negative result, 1.3% had high-...