OBJECTIVE To critically evaluate the P to oocyte (O) ratio (P/O) in the prediction of live birth in assisted reproductive technology (ART) cycles. DESIGN Retrospective cohort study. SETTING Not applicable. PATIENT(S) A total of 7,608 fresh autologous ART ET cycles. INTERVENTION(S) None. MAIN OUTCOME MEASURE(S) Live birth. RESULT(S) Generalized estimating equation (GEE) models and re...

BACKGROUND Over the past 10 years, there has been a significant increase in the use of assisted reproductive technologies in Canada, however, little is known about the overall prevalence of infertility in the population. The purpose of the present study was to estimate the prevalence of current infertility in Canada according to three definitions of the risk of conception. METHODS Data from t...

In a non-matched case-control study using data from two large national cohort studies, we investigated whether indicators of child health and development up to 7 years of age differ between children conceived using assisted reproductive technology (ART), children born after sub-fertility (more than 24 months of trying for conception) and other children. Information on ART use/sub-fertility was ...

One of the plots of the Canadian science fiction thriller Orphan Black involves a scheme to create dozens of siblings by harvesting the eggs of one woman, fertilizing them with the sperm of a single man, and implanting them for gestation in dozens of apparently willing surrogates.¹ The casualness of the procedure speaks to how comfortable we have all become with reproduction by technology. Yet ...

n little more than two decades, the subject of multiple pregnancy has evolved from an obstetric curiosity to an issue of international medical and social concern. The overall number of multiple pregnancies has increased dramatically, not only for twins, but also for triplets and higher-order births. In addition, physicians and society are now concerned with a previously unknown type of multiple...

Assisted reproductive technology (ART) has revolutionized the management of subfertility as many couples who previously had no hope of achieving a pregnancy are able to do so. Several factors contribute to the successful outcome of assisted conception. The period of waiting for the pregnancy test after assisted conception could be very crucial to the patient. One outcome of assisted conception ...

The ART of Life: IVF or Child Adoption? This paper analyzes the effects of child adoption on the utilization of assisted reproductive technology (ART) in the US. Using state-level longitudinal data for 1999-2006, we show that ART use is responsive to changes in adoption markets. Controlling for state-specific fixed effects, the estimated elasticity of ART cycles performed with respect to child ...

INTRODUCTION This study is part of a longitudinal cohort undertaken in both women and men to describe live birth outcome after undergoing assisted reproductive technology (ART) treatment in a clinical setting. Another objective was to follow women and men living with children from other alternatives after ART, such as adoption. MATERIAL AND METHODS A total of 439 (80.5%) women and 423 (77.6%)...

Dear Editor: Upon reading the recently published article entitled “Adverse pregnancy outcomes with assisted reproductive technology in non-obese women with polycystic ovary syndrome: a case control study” [1], we were compelled to point out that the study design does not conform to the principles of a case-control study. The authors state that the aim of the study was to compare the prevalence ...