نتایج جستجو برای: associated lipocalin ngal

تعداد نتایج: 1522278  

Journal: :Türk biyokimya dergisi 2022

Abstract Objectives This study was aimed to investigate the diagnostic values of serum levels asprosin and neutrophil gelatinase-associated lipocalin (NGAL) in Retinopathy prematurity (ROP) assess role these biomarkers on development progression condition. Methods carried out from April 2020 February 2021 department ophthalmology a tertiary hospital Turkey. Thirty patients diagnosed with ROP 30...

Journal: :Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2015
Francesca Martino Elisa Scalzotto Davide Giavarina Maria Pia Rodighiero Carlo Crepaldi Sonya Day Claudio Ronco

BACKGROUND Peritoneal dialysis (PD) is frequently complicated by high rates of peritonitis, which result in hospitalization, technique failure, transfer to hemodialysis, and increased mortality. Early diagnosis, and identification of contributing factors are essential components to increasing effectiveness of care. In previous reports, neutrophil gelatinase-associated lipocalin (NGAL), a lipoca...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2014
Søren Lindberg Jan S Jensen Rasmus Mogelvang Sune H Pedersen Søren Galatius Allan Flyvbjerg Nils E Magnusson

OBJECTIVE Neutrophil gelatinase-associated lipocalin (NGAL) is a glycoprotein stored in granules of neutrophil leukocytes participating in inflammatory and atherosclerotic processes and possibly plaque rupture. Despite the putative role of NGAL in atherosclerosis and acute myocardial infarction, human studies of plasma NGAL are still limited. APPROACH AND RESULTS We prospectively followed 559...

Journal: :Clinical biochemistry 2013
Johanna Helmersson-Karlqvist Johan Arnlöv Anders Larsson

OBJECTIVES The number of clinical studies evaluating the new tubular biomarker urinary neutrophil gelatinase-associated lipocalin (U-NGAL) in urine are increasing. There is no consensus whether absolute U-NGAL concentrations or urinary NGAL/creatinine (U-NGAL/Cr) ratios should be used when chronic tubular dysfunction is studied. The aim was to study the biological variation of U-NGAL in healthy...

2015
Raffaele Serra Lucia Butrico Raffaele Grande Girolamo Domenico Placida Paolo Rubino Ugo Francesco Settimio Gennaro Quarto Maurizio Amato Ermenegildo Furino Rita Compagna Bruno Amato Luca Gallelli Stefano de Franciscis

INTRODUCTION An arteriovenous fistula (AVF) for placed for hemodialysis may be burdened by one particular complication-the formation of a venous aneurysm. It has been shown that matrix metalloproteinases (MMPs) and neutrophil gelatinase-associated lipocalin (NGAL) could represent markers of disease in both venous and arterial vessels. MATERIALS AND METHODS This case study reports a rare case ...

Journal: :Clinical journal of the American Society of Nephrology : CJASN 2010
David R McIlroy Gebhard Wagener H Thomas Lee

BACKGROUND AND OBJECTIVES Neutrophil gelatinase-associated lipocalin (NGAL) is rapidly released by renal tubules after injury, potentially allowing early identification of acute kidney injury (AKI) after cardiac surgery. However, the diagnostic performance of NGAL has varied widely in clinical studies, and it remains unknown what factors modify the relationship between NGAL and AKI. We hypothes...

2012
Thomas L. Nickolas Catherine Forster Meghan E. Sise Nicholas Barasch David Solá-Del Valle Melanie Viltard Charles Buchen Shlomo Kupferman Maria Luisa Carnevali Michael Bennett Silvia Mattei Achiropita Bovino Lucia Argentiero Andrea Magnano Prasad Devarajan Kiyoshi Mori Hediye Erdjument-Bromage Paul Tempst Landino Allegri Jonathan Barasch

The type and the extent of tissue damage inform the prognosis of chronic kidney disease (CKD), but kidney biopsy is not a routine test. Urinary tests that correlate with specific histological findings might serve as surrogates for the kidney biopsy. We used immunoblots and ARCHITECT-NGAL assays to define the immunoreactivity of urinary neutrophil gelatinase-associated lipocalin (NGAL) in CKD, a...

Journal: :Iranian journal of kidney diseases 2017
Atefeh Ordooei Javan Jamshid Salamzadeh Shervin Shokouhi Zahra Sahraei

INTRODUCTION Nephrotoxicity has been a concern with new dosing regimens of colistin. This study was designed to compare nephrotoxicity of high dose and conventional dose of colistin and the ability of detecting it using neutrophil gelatinase-associated lipocalin (NGAL). MATERIALS AND METHODS A randomized clinical trial was carried out on 40 patients with multidrug-resistant gram-negative infe...

2015
Vanessa Abella Morena Scotece Javier Conde Rodolfo Gómez Ana Lois Jesús Pino Juan J. Gómez-Reino Francisca Lago Ali Mobasheri Oreste Gualillo

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a secreted glycoprotein that belongs to a group of transporters of small lipophilic molecules in circulation. LCN2 has been recently characterized as an adipose-derived cytokine. This adipokine is believed to bind small substances, such as steroids and lipopolysaccharides, and has been reported to have roles...

2015
Korhan Soylu Gökhan Aksan Gökay Nar Metin Özdemir Okan Gülel Sinan İnci Aytekin Aksakal Ayşegül İdil Soylu Özcan Yılmaz

OBJECTIVE Neutrophil gelatinase-associated lipocalin (NGAL) is a novel inflammatory marker that is released from neutrophils. In this study, we evaluated the correlation between serum NGAL level and clinical and angiographic risk scores in patients diagnosed with non-ST elevation acute coronary syndrome (NSTE-ACS). METHODS Forty-seven random NSTE-ACS patients and 45 patients with normal coron...

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