OBJECTIVES This study evaluated the cost-effectiveness of administering prophylactic intravenous (IV) amiodarone therapy to patients undergoing cardiac surgery according to their predicted risk of postoperative atrial fibrillation. BACKGROUND Atrial fibrillation (AF) is a common complication of cardiovascular surgery that is associated with a significant increase in hospitalization costs. Int...

Atrial fibrillation (AF) is the most common arrhythmia in clinical settings (Fuster et al., 2001), and it is often associated with congestive heart diseases (Issac et al., 2007). Many studies in both laboratory and clinical settings have sought to analyze the mechanisms of AF, develop treatments based on these mechanisms, and examine atrial remodeling in chronic AF. The aim of this paper is to ...

During a redo procedure for paroxysmal atrial fibrillation (AF) recurrence, mitral isthmus-dependent atrial tachycardia due to a gap in the previous line and rate-dependent slow conduction in sinus rhythm were demonstrated. After initial achievement of mitral isthmus block, adenosine reproducibly triggered conduction recovery and initiated AF. Further ablation led to AF termination and stable b...

BACKGROUND Atrial fibrillation (AF) leads to structural and neural remodeling in the atrium, which enhances AF complexity and perpetuation. Renal denervation (RDN) can reduce renal and whole-body sympathetic activity. Aim of this study was to determine the effect of sympathetic nervous system modulation by RDN on atrial arrhythmogenesis. METHODS AND RESULT Eighteen goats were instrumented wit...

Introduction: Atrial fibrillation is associated with increased C-reactive protein level and other acute phase reactant (fibrinogen level, interleukin 2, 6, 8, and others), which raise the question of the role of inflammation in this condition? Aim of the Work: To asses the relation between atrial fibrillation and serum inflammatory biomarkers (IL-6 & Hs CRP). Study Design: The study included th...

OBJECTIVES We sought to investigate the imaging of the left atrial (LA) muscular bundle and the relationship between the bundle and inducibility of tachyarrhythmia after pulmonary vein isolation (PVI). BACKGROUND Noninducibility is used as a clinical end point of atrial substrate ablation after PVI. However, little is known about the role of the LA muscular bundles in tachyarrhythmia after PV...

Atrial fibrillation (AF) is a common complication after cardiac surgery, its frequency ranges between 25– 40% reaching upto 50% following bypass surgeries as reported in previous studies. Several reports have indicated that postoperative AF is associated with significantly increased morbidity and mortality. 2 Our primary aim in this study was to investigate the effectiveness of prophylactic mag...

Background Left ventricular late gadolinium enhancement (LV-LGE) is a known incidental cardiac magnetic resonance (CMR) finding in atrial fibrillation (AF) patients and has recently been associated with increased mortality [1]. While LV-LGE is an indicator of poor prognosis in patients with cardiomyopathy, data on the clinical significance of incidental findings of LV-LGE in AF patients is stil...

Atrial fibrillation (AF) is a very undesirable, but unfortunately a common arrhythmia following coronary artery bypass graft (CABG) surgery, occurring in up to 40% of patients1. There is an increase in hospital stay2 and adds to the overall cost of the surgery. Atrial fibrillation occurrence may identify a subset of patients with reduced survival3. Prevention of AF therefore would have a signif...

Association of AmiodaroneUseWith Acute Pancreatitis in PatientsWith Atrial Fibrillation: ANested Case-Control Study Amiodarone hydrochloride is an antiarrhythmic drug frequently used in the treatment of atrial fibrillation (AF). Isolated reports1-3 have suggested that use of amiodarone may cause acute pancreatitis. To our knowledge, this potential adverseeffectof amiodaronehasnotbeenexplored in...