Background: Psoriasis is a chronic autoimmune skin disorder with relapsing erythematous scaling plaques and joint or nail involvement. A greater occurrence of other autoimmune diseases has been reported in these patients. Additionally, their family members are more likely to be diagnosed with psoriasis. The aimof this study is to assess the prevalence of certain autoimmune diseases in first deg...

Autoimmune pancreatitis (AIP) has been widely presumed to be an autoimmune disease that is characterized by elevated IgG and/or IgG4, the presence of autoantibodies, and an infiltration of lymphocytes and plasma cells with fibrosis. However, no detailed immunological studies have been published. To define immunological changes in AIP in detail, and to review evidence for autoimmunity which may ...

A 48 Year-old woman had symptoms of thyrotoxicosis which disappeared spontaneously within two months. She was diagnosed as case of silent thyroiditis on the basis of both the clinical course and the laboratory data such as low uptake of radioactive Iodine and Technesium. She also had petechia in her arms which were diagnosed as an idiopathic thrombocytopenic purpura (I.T.P.). This case would se...

autoimmune hepatitis is a chronic hepatitis that occurs in children and adults of all ages. diagnosis is based upon characteristic serologic and histologic findings and the exclusion of other forms of chronic liver disease. guidelines issued by the aasld suggest the following diagnostic considerations: the diagnosis should be made in patients with compatible clinical signs, symptoms, and labora...

case presentation we herein describe a case of a 7 year-old child affected by an overlap syndrome between type 2 autoimmune hepatitis and small duct primary sclerosing cholangitis. although characterized by a severe onset, the disease showed a good response to treatment with prednisone and azathioprine. conclusions the association of type 2 autoimmune hepatitis and small duct primary cholangiti...

INTRODUCTION Autoimmune diseases are chronic conditions initiated by the loss of immunological tolerance to self-antigens. They constitute heterogeneous group of disorders, in which multiple alterations in the immune system result in a spectrum of syndromes that either target specific organs or affect the body systematically. Recent epidemiological studies have shown a possible shift of one aut...

Pemphigus vulgaris (PV) is a potentially fatal autoimmune mucocutaneous blistering disease. Although PV occurs predominantly in adulthood, in the 3rd to 5th decades of life, there have rarely been reports of childhood cases which are often misdiagnosed. It presents as oral blisters that rupture rapidly and progress to painful erosions. Most patients develop cutaneous flaccid blisters that ruptu...

introduction coexistence of wilson’s disease and autoimmune hepatitis has been rarely reported in english literature. in this group of patients, there exist features of both diseases and laboratory and histopathological studies may be misleading. medical treatment for any of these entities, per se, may result in poor response. therefore, by considering the acute hepatitis resembling wilson’s di...