Visceral leishmaniasis (VL) or Kala-azar is a protozoal disease, which was previously regarded as one of the most neglected tropical diseases. Management of this disease is quite difficult, because it is said to affect the poorest of the poor. Previously Sodium Stibogluconate (SSG) was regarded as the gold standard treatment for VL. But due to the increasing unresponsiveness, to this drug vario...

The performances of two rapid tests and a standard serological test for the diagnosis of visceral leishmaniasis (VL) were compared using sera from 193 patients with VL and 85 controls. The Kala-Azar Detect(®), IT-LEISH(®) and IFI-LH(®) assays showed sensitivities of 88.1%, 93.3% and 88.6%, respectively, and specificities of 90.6%, 96.5% and 80%, respectively. The sensitivity values were similar...

Visceral leishmaniasis (VL) is a severe and often fatal form of caused by Leishmania donovani in the Indian sub-continent. Post Kala-azar Dermal Leishmaniasis (PKDL) late cutaneous manifestation VL, typically occurring after apparent cure but sometimes even without prior history VL India. PKDL serves as significant yet neglected reservoir infection plays crucial role transmission disease, posin...

Leishmaniasis is caused by the infection of haemoparasite „Leishmaniadonovani’. Clinically it can present as Cutaneous Leishmaniasis (CL), Mucocutaneous Leishmaniasis (MCL) and Visceral Leishmaniasis (VL). In India it is a major health problem in the North & Central regions of India and is infrequently reported from western India. However, we encountered two clinically suspected cases of Leishm...

Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found in the spleen, liver, and bone marrow. Patients with active disease typically exhibit marked immunosuppression, lack reactivity to the Leishma...

Visceral leishmaniasis (VL) or Kala-azar (KA) is a communicable disease caused by Leishmania donovani named after the discoverers, Leishman and Donovan both of whom reported on the organism simulataneously, Leishman from London in May, 1903 and Donovan in July, 1903. Except for Australia, it is endemic in many places in China, Africa, Southern Europe, South America, Russia and India where it is...

Introduction: Leishmaniasis is a complex parasitic disease with various epidemiological and clinical features. Visceral leishmaniasis (VL) can be extremely fatal in untreated cases. The objective of this study was to assess the epidemiological and clinical aspects of the disease in children with VL in Kerman province during 1991-2006. Method: In a descriptive-analytical survey, medical file...

visceral leishmaniasis (vl) is one of the most important parasitic diseases which is endemic in different parts of iran. serological studies were conducted by direct agglutination test (dat) on 12144 human serum samples, collected from four geographical zones of iran. sero prevalence, geographical distribution, clinical signs and symptoms for human visceral leishmaniasis based on dat for the pe...

INTRODUCTION Visceral leishmaniasis (VL; kala-azar) is a serious zoonosis that can be lethal, especially in untreated patients. Due to the fact that the State of Ceará is still an important area of transmission of VL, and based on the constant reports of the urbanization process of the disease in the country, it was necessary to monitor the occurrence of cases of leishmaniasis through epidemiol...