This study evaluated the effects of azathioprine in combination with low-dose prednisolone in the management of patients with intractable autoimmune hepatitis. Thirteen patients with intractable autoimmune hepatitis who had an incomplete or arrested response to conventional prednisolone therapy, or who relapsed during prednisolone maintenance therapy were additionally administered 50 or 100 mg/...

BACKGROUND AND OBJECTIVES Treatment with azathioprine within 3 months of remission induction with cyclophosphamide is a common treatment strategy for patients with ANCA-associated vasculitis. This study comprised patients undergoing long-term follow-up who were randomly allocated to azathioprine after 3-6 months or after 12 months of cyclophosphamide treatment. DESIGN, SETTING, PARTICIPANTS, ...

Induction of lactic dehydrogenase (LDH) antibody with porcine LDH in L1210 leukemia-bearing DBA/2 mice can induce remissions of the disease. The concurrent, limited use of a cytotoxic agent (azathioprine) in combination with LDH has been investigated and found to be advantageous in terms of obtaining a greater number of prolonged remis sions (over 150 days) than does the use of LDH alone. The p...

While immunosuppressive agents are used widely in the management of Crohn's disease, their efficacy has not been well established in randomised controlled trials. This study was designed to examine whether azathioprine increases remission rate when used in conjunction with a diminishing dose regimen of prednisolone over a period of 12 weeks. It further examined whether azathioprine offers any t...

Induction of lactic dehydrogenase (LDH) antibody with porcine LDH in L1210 leukemia-bearing DBA/2 mice can induce remissions of the disease. The concurrent, limited use of a cytotoxic agent (azathioprine) in combination with LDH has been investigated and found to be advantageous in terms of obtaining a greater number of prolonged remis sions (over 150 days) than does the use of LDH alone. The p...