objective: to assess the effects of platelet rich plasma (prp) with chitosan biodegradable film on full thickness wound healing in rat. methods: this was an experimental study being performed in 2015 during a 4-month period. twenty-four male white wistar rats were divided into four groups of 12 rats each, randomly: control group (sham) with creation of wounds and no treatment, prp group with cr...

Platelet-derived Growth Factors (GFs) are biologically active peptides that enhance tissue repair mechanisms such as angiogenesis, extracellular matrix remodeling, and cellular effects as stem cells recruitment, chemotaxis, cell proliferation, and differentiation. Platelet-rich plasma (PRP) is used in a variety of clinical applications, based on the premise that higher GF content should promote...

BACKGROUND Washing of platelets is an important procedure commonly used for experimental studies, e.g. in cardiovascular research. As a known phenomenon, responsiveness to adenosine diphosphate (ADP) is reduced in washed platelets, although underlying molecular mechanisms-potentially interfering with experimental results-have not been thoroughly studied. OBJECTIVES Since ADP mediates its effe...

Introduction Autologous plasma-rich platelet (PRP) is a human platelet concentrated product which is in low volume of plasma. Using PRP in rejuvenation and resolution of some cosmetic problems has been already popular in many countries and also in Iran. As no study performed in this field in Iran and regarding the high prevalence of using PRP in society with no validate references in the case ...

Aim: To compare the quality of the PC's prepared by three methods i.e Platelet Rich Plasma (PRP), Buffy Coat (BC) and Apheresis method as per the departmental SOP based on DGHS criteria. Material & Methods: Four platelet concentrates prepared by each of the three methods were assessed every month for the following quality parameters Swirling, Volume, Platelet count, WBC count and pH. 48 PC of e...

Platelet-rich plasma (PRP) is a new application of tissue engineering and a developing area for clinicians and researchers. It is a storage vehicle of growth factors (GFs) such as platelet-derived growth factor (PDGF)- AA, -BB, -AB; transforming growth factor (TGF)-beta1 and -2; platelet-derived epidermal growth factor (PDEGF); platelet-derived angiogenesis factor (PDAF); insulin growth factor-...

background and aims: plasma rich in growth factors (prgfs) has been recently proposed as an aid to enhance regeneration of osseous and epithelial tissues in oral surgery. the purpose of this study was to determine the effect of local application of platelet rich plasma (prp) on implant stability measured by periotest. materials and methods: a total of 24 implants were placed in mandible of 12 l...

conclusions it seems that applying prp is an effective therapeutic approach for wound healing, and faster wound healing is expected due to the presence of more platelets and growth factors. results at the end of study, the prp group showed a greater reduction in the edema ecchymosed discharge approximation (reeda) score compared to the control group (85.5% reduction in the prp group; 72% in the...

BACKGROUND Platelet-rich plasma (PRP) has been suggested as a therapeutic intervention for female androgenetic alopecia. OBJECTIVE To perform a pilot study on the effect of PRP scalp injections in women with female androgenetic alopecia. MATERIALS AND METHODS This double-blind, multicenter, placebo-controlled study compared the effect of PRP with that of saline placebo as scalp injection. T...

As use of autologous platelet-rich plasma (PRP) and platelet-poor plasma (PPP) increases for intraoperative care of a variety of patients, it is important for perioperative nurses to recognize their benefits. Autologous PRP may decrease postoperative drainage, reduce narcotic requirements, and facilitate an early return to mobility. Postoperatively, patients should experience fewer complication...