The present study examined the hepatotoxicity and nephrotoxicity of morphine and illicit street heroin and their amelioration by a standardized methanolic extract of Bacopa monnieri (L.) (mBME) in rats. Morphine or street heroin was administered at a dose of 20 mg/kg for 14 and 21 days. mBME (40 mg/kg) or ascorbic acid (50 mg/kg) was administered two hours before morphine or street heroin. High...

BACKGROUND Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed in blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the t...

Bacopa monnieri (BM; Family: Scrophulariaceae), also referred as Brahmi or Jalbrahmi has been used for centuries in Ayurvedic system of medicine as a brain tonic, memory enhancer, revitaliser of sensory organs, anti-anxiety, cardio-tonic, diuretic, antidepressant and anticonvulsant agent, and the pharmacological actions are mainly attributed to the saponin compounds present in the alcoholic ext...

The Development and Assessment of a Herbal Floating Tablet for Peptic Ulcer Disease. goal creating herbal floating tablet is to extend the drugs duration in gastrointestinal tract. This will increase bioavailability result greater absorption than with convectional dose form. Due its gastro-retentive feature, medicine remains at site inflammation longer amount time, resulting more targeted actio...

Pharmacognosy Research,2023,15,3,410-454.DOI:10.5530/pres.15.3.045Published:June 2023Type:Review ArticleAuthors:Sumanta Mondal, Kausik Bhar, Prasenjit Naresh Panigrahi, Suvendu Kumar Sahoo, Pydi Swetha, Subhadip Chakraborty, Nooka Yaswanth Teja, and Neha Parveen Author(s) affiliations:Sumanta Mondal1,*, Bhar1, Mondal2, Panigrahi1, Sahoo1, Swetha1, Chakraborty1, Teja1, Parveen1 1Department of Ph...