نتایج جستجو برای: bacterial reverse mutation assay
تعداد نتایج: 777536 فیلتر نتایج به سال:
BACKGROUND Silica dioxide (SiO2) has been used in various industrial products, including paints and coatings, plastics, synthetic rubbers, and adhesives. Several studies have investigated the genotoxic effects of SiO2; however, the results remain controversial due to variations in the evaluation methods applied in determining its physicochemical properties. Thus, well characterized chemicals an...
The bacterial GlgE pathway is the third known route to glycogen and only one present in mycobacteria. It contributes virulence of Mycobacterium tuberculosis . involvement biosynthesis was discovered twenty years ago when phenotype a temperature-sensitive smegmatis mutation rescued by glgE gene. evidence at time suggested coded for glucanase responsible hydrolysis glycogen, stark contrast with r...
Two A/-nitroso bile acid conjugates, A/-nitrosotaurocholic acid and /V-nitrosoglycocholic acid, were tested for mutagenicity by forward mutation assay in Salmonella typhimurium TM 677 and in diploid human lymphoblasts, line TK6. /V-Nitrosoglycocholic acid and A/-nitrosotaurocholic acid showed similar concentra tion-response curves in the bacterial assay with statistically significant mutant fra...
results using these two sets, we identified h1069q mutation in four patients, c.2335t > g mutation in three, c.3061-1g > a splice site mutation in five, c.3305t > c mutation in one, and c.3809a > g mutation in two patients. conclusions the multiplex arms assay used in this study can be an efficient, reliable, and cost effective method as a primary screen for patients with wilson disease. patien...
Aim: Fermotein is an innovative single-cell protein obtained from fermentation of the filamentous fungus Rhizomucor pusillus. Like other fungi, a lack information on this species exists to assess its safety for human consumption. The capability induce gene mutations or structural and numerical chromosomal aberrations derived products has never been studied before. objective current study was in...
A patient presenting with concomitant epidermal growth factor receptor (EGFR) mutation and anaplastic lymphoma kinase (ALK) translocation is rare. We report a non-small cell lung cancer (NSCLC) patient with concomitant ALK rearrangement and exon 19 (E746-A750del) EGFR mutation. The ALK rearrangement was confirmed not only in the primary tumor biopsy specimen, but also in the pleural effusion ce...
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