background: phenol is an estrogenic and toxic compound and people are widely exposed to it, in different ways.  objectives: the aim of this study was to determine  the  negative effects of phenol on the fertility of male mice, by investigating sperm parameters including viability, motility, fertility rates and daily sperm production (dsp). methods: a total of 106 adult nih mice were divided int...

reports indicate that one of the causes of harmful to the genital system, especially the testes is stress. result of damage to testicular quality certainly will affect the quality of sperm fertility. stress could be created secondarily after some pathological conditions such as neurological diseases or environmental factors. one of the causes of stress could be scary voices, such as cat voice f...

background there is still no suitable mice model that can completely mimic the human fulminant hepatitis, which sets a block for drug effect evaluation and mechanism researching of human fulminant hepatitis. objectives the aim of this study was to establish an animal model able to mimic the main features of human fulminant hepatitis. materials and methods dimethylnitrosamine (dmn) was peritonea...

conclusions our results demonstrated the promising prophylactic and therapeutic effects of propranolol against t. gondii infection. propranolol also increases the efficacy of pyrimethamine in combination therapies. results in the pre-treatment group, results showed that propranolol at 2 and 3 mg/kg combined with pyrimethamine was more effective in inhibiting growth of tachyzoites (86% and 98%, ...

background: indisputable population exposure to widespread electromagnetic fields, has grown concerns over the probable health effects of these fields. objective: the present study was aimed to examine the possible effects of 50 hz extremely low frequency electromagnetic field (elf-emf) exposure on the number and quality of mice blastocysts. materials and methods: in present study, 66 nmri preg...

background and aims: this study examined sub-chronic effects of methamphetamine (meth) on the stereological parameters in the cornu ammonis (ca) of the hippocampus in adult mice. materials and methods: fifteen adult male mice, eight weeks old, were randomly divided into three groups: receive saline (controls), or low-dose (ld) 2.5 mg/kg meth, or high-dose (hd) 25 mg/kg meth, via daily intraperi...

the effects of chronic administration of lithium, on acute toxicity of chlorpromazine (cpz) in male albino mice was studied and the ldso values were determined from dose-probit curves. tfie results showed that in lithium pretrealed animals (anmials consumed drinking water containing 600mg/l lithium chloride for 10 days) the ld50 value (the dose corresponding to probit 5) of cpz increased signif...

background: in the present investigation radiation and cadmium induced biochemical changes in the kidney of swiss albino mice have been studied. materials and methods: for this purpose, adult male swiss albino mice (6-8 weeks old) were divided into four groups. group i (sham-irradiated), group ii (treated with cdcl2 solution 20 ppm), group iii (irradiated with 1.25, 2.5 and 5.0 gy gamma rays), ...

background: saccharin is an artificial non-caloric sweetener that used to sweeten products such as drinks, candies, medicines, and toothpaste, but our bodies cannot metabolize it. sodium saccharin is considered as an important factor in tumor promotion in male rats but not in humans. objective: the objective of this study was to investigate the effect of saccharin consumption on sperm parameter...