background : this study retrospectively evaluated the prognostic factors and treatment outcome of patients with hormone-refractory prostate cancer who received chemotherapy. methods :we reviewed records of hormone-refractory prostate cancer patients who received chemotherapy between december 2004 and may 2011 at the clinical oncology and nuclear medicine department, mansoura university and the ...

Objective: Although cancer chemotherapy has been used for more than seventy years, its definitive mechanism of action is not known. Many studies indicate that beyond DNA the collagen connective tissue matrix also affected. This database analysis aims to determine extent versus perception in scientific papers indexed under PubMed. Materials and methods: The PubMed scanned on September, 15, 2021 ...

background : chemotherapy induced nausea and vomiting is an added distress to patients burdened by the illness. in an effort to tackle the emetogenic potential of the agents, guidelines have been proposed to maintain uniformity in prescription and improvement in patient tolerance; but their utility and practice is not consistent. the aim of this clinical audit was to assess the antiemetic.pract...

with the success achieved in the interruption of the transmission of bilharziasis by snail control in most endemic areas of iran, mass-chemotherapy has been used extensively for reducing the number of cases in various villages. niridazol was chosen for this purpose after a screening of several drugs. eight thousand eight .l1undred seventy-four cases in 259 localities were treated from 1966 to t...

purpose: to introduce a case of neglected advanced retinoblastoma. case report: a 6 year old girl presented with a large orbital mass enlarging over her cheek on the right side. she underwent exenteration and histopathologic evaluation. a diagnosis of retinoblastoma was made with free margins. this case presents a rare form of retinoblastoma with extensive local progression but no metastasis or...

introduction: breast cancers are divided into at least 4 sub types on the basis of gene expression profiles and expression of receptors as measured by ihc (immunohistochemical). triple negative breast cancer (tnbc) is more chemosensitive yet, it is much harder to detect than other sub types. at present lack of highly effective therapeutic targets for tnbc, leaves standard chemotherapy, as the o...

conclusions this study demonstrates that using either honey or normal saline can reduce the rate and severity of chemotherapy induced mucositis. background oral mucositis is a frequent problem after high-dose chemotherapy which could impair patient’s quality of life, higher rates of infections, and delay in subsequent chemotherapy. objectives the present study was performed to assess the effect...

In epithelial ovarian cancer (EOC), intraperitoneal (IP) administration of chemotherapy is an effective first-line treatment and may improve outcomes, compared with intravenous (IV) chemotherapy. We used Kaplan-Meier survival analysis to compare long-term survival between propensity score-matched patients with advanced EOC receiving IP (n = 34) vs. IV (n = 68) chemotherapy. Additionally, clinic...

Currently, platinum-based combination chemotherapy is the standard first-line chemotherapy for non-small-cell lung cancer (NSCLC). Historically, platinum-based chemotherapy has been recommended for up to six cycles even for responders, and second-line chemotherapy has been considered when disease progression is confirmed. In spite of extensive investigations into maintenance chemotherapy, no po...