widespread use of pharmaceuticals has resulted in mixture concentrations ranging from mg/l in effluent to µg/l concentrations in surface water. in a 2008 study, 13 pharmaceuticals, ranging in amounts from 0.0028 to 0.1757 µg/l, were identified in the tennessee river, usa and its tributaries. in order to address the need for risk assessment of environmentally relevant pharmaceutical mixtures, da...

objective(s):cefixime (cfx), is a semi-synthetic third-generation oral cephalosporin antibiotic that is prescribed for the treatment of susceptible infections. there are some procedures for the determination of cfx in pharmaceutical formulations and biological samples. herein a spectrofluorimetric method was proposed for cfx determination based on the fluorescence quenching of terbium-danofloxa...

After the boom of pharmacological research during the 1950s, mainly as a result of the screening technique, the identification of active molecules, their reshaping by means of pharmaco-chemical drug design, and the creation of extremely efficacious and successful medicines, the pharmaceutical world sought a new source of inspiration. Such biota as the tropical forest, a quantity of plants credi...

The pharmaceutical industry suffers from increasing counterfeit rates. Federal law restrictions force manufacturers to guarantee authenticity of their products. RFID technology can be used as foundation for an integer and counterfeit-resistant pharmaceutical supply chain. In the given paper, we introduce an architecture optimized for storing and searching of RFID data. It is specifically design...

Background: Nowadays pharmacists should be involved in patients care and providing pharmaceutical care more than before, but still there is a gap between standard of care and pharmacy practice in pharmacies. Objective: In this study we aimed at evaluating the pharmacists experiences and attitudes about ethical professional practice in pharmacies. Setting: The study was conducted in the Tehran ...

OBJETIVE To analyze the relationship between access to medicines by the population and the institutionalization of pharmaceutical services in Brazilian primary health care. METHODS This study is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - S...

The extensive use of polymers in medical and pharmaceutical applications including particularly packaging, medical devices, drug carriers and coatings has caused a substantial demand for the proper plasticizers. Although there are many plasticizers used in the chemical industry, only a few of them have been approved for pharmaceutical applications. The natural-based plasticizers characterized b...

Pharmaceutical industry is currently undergoing a transient phase with new orientation. Loss of financial resources, presence of new therapeutic agents and increasing cost of research and development have called for a full.scale restructuring within the pharmaceutical industry to retain even the most basic competitiveness. The development of new technologies has been as one way out of the dile...

in this work, the optimization calculations were carried out on quetiapine hemifumarat, 4, and its analogues, 1-5. these calculations were carried out using the b3lyp/6-31g(d) level of theory. the dft calculations clarified a boat structure for dibenzothiazepine moiety of the molecule which piperazine moiety has a chair conformation. thermal energies (e), enthalpies (h), and free energies (g) o...