Chandraprabha vati, an Ayurvedic formulation, was studied for its effect in experimental prostatic hyperplasia induced by testosterone injection s.c for 21 days in rats and inflammation induced in rat hind paw by carrageenan injection s.c. The results showed that Chandraprabha vati at dosage of 100, 200 and 400 mg/kg orally for 21 days showed significant reduction of prostatic hyperplasia as in...

Trans urethral resection of prostate (TURP) is the most frequently performed surgical treatment for patients diagnosed with benign prostate hyperplasia. This retrospective observational study was design to evaluate the occurrence and the characteristics of incidental prostate cancer (IPC), in patients underwent TURP for clinically benign disease. In histopathology of TURP specimens 14.9% showed...

A PHASE II STUDY ASSESSING THE SAFETY AND EFFICACY OF A SINGLE TREATMENT OF 100 U, 200 U, or 300 U BOTOX® COMPARED WITH PLACEBO INJECTED INTO THE PROSTATE TO TREAT LOWER URINARY TRACT SYMPTOMS (LUTS) IN PATIENTS DUE TO BENIGN PROSTATIC HYPERPLASIA Trial ID: 191622-517-05 Coordination: CMX Research Inc. Trial design: A phase II study assessing the safety and effi cacy of a single treatment of BO...

The total area of the acini and the luminal area was statistically significantly greater in BPH. In normal and hyperplastic prostates, respectively, the total mean ( SD ) area (mm 2 ) of the acini was 0.041 (0.007) and 0.056 (0.016), of the lumen was 0.016 (0.003) and 0.036 (0.013), and of the epithelium was 0.025 (0.004) and 0.019 (0.003) (all P < 0.001). There was no statistically significant...

The results of an investigation show that there is no statistically significant excess of blood group A in cases of carcinoma of the oesophagus or in cases of benign prostatic hyperplasia.

BACKGROUND Despite ethical imperatives, informing research participants about the results of the studies in which they take part is not often performed. This is due, in part, to the costs and burdens of communicating with each participant after publication of the results. METHODS Following the closeout and publication of a randomized clinical trial of saw palmetto for treatment of symptoms of...

Benign prostatic hyperplasia (BPH) is a common disease, not only in Asia but worldwide. The spectrum of disease may vary in differently region, but the basic pathophysiology is the same. To manage the disease, we need to define what it is, before the diagnosis. Management would be according to the basic fundamentals of good clinical practice. That is, whatever we do is for the benefit of the pa...