The common three-toed sloth is a widespread species, but the location and the observation of its individuals are greatly hindered by its biological features. Their camouflaged pelage, its slow and quiet movements, and the strictly arboreal habits resulted in the publication of sparse, fragmented and not patterned information on the common sloth behaviour. Thus, herein we propose an updated stan...

The SLAC 40” HBC was exposed to a 4.3 BeV positron annihilation radiation. Results are presented on reactions containing no neutrals and one neutral particle in the final state. For w--pop and w”p we find cross sections of (19.2 -I 1.2)pb and (2.8 st .5)pb respectively . Assuming Vector Dominance, we determine the V”p cross sections. Evidence for other resonant states is presented, in particula...

BACKGROUND In the FIRE-3 trial, overall survival (OS) was significantly longer in patients treated with FOLFIRI plus cetuximab (C-mab) than in those treated with FOLFIRI plus bevacizumab (Bev), but progression-free survival (PFS) was not significantly different. This may be associated with the deepness of response (DpR) in patients treated with FOLFIRI plus C-mab. We aimed to evaluate the relat...

PURPOSE To evaluate the time course and association with survival of anatomic lesion volumes and diffusion imaging parameters for patients with newly diagnosed glioblastoma who were treated with radiation and concurrently with either temozolomide and enzastaurin (TMZ+enza cohort) or temozolomide, erlotonib, and bevaciumab (TMZ+erl+bev cohort). MATERIALS AND METHODS Regions of interest corresp...

In principle, there exists a second invariant in the fourth-order derivatives of ~. However, in a system with translational invariance this term is identical with that given in (1). See K. G. Wilson and J. Kogut, Phys. Bep. 12C, 75 (1974); S.-k. Ma, Bev. Mod. Phys. 45, 589 (1973); M. E. Fisher, Bev. Mod. Phys. 46, 597 (1974); and A. Aharony, in "Phase Transitions and Critical Phenomena, " edite...

Gemcitabine (Gem) has limited clinical benefits in pancreatic ductal adenocarcinoma (PDAC). The present study investigated combinations of gemcitabine with antiangiogenic agents of various mechanisms for PDAC, including bevacizumab (Bev), sunitinib (Su) and EMAP II. Cell proliferation and protein expression were analyzed by WST-1 assay and Western blotting. In vivo experiments were performed vi...

PURPOSE Evaluate conversion rate of patients with unresectable colorectal-liver metastasis to complete resection with hepatic-arterial infusion plus systemic chemotherapy including bevacizumab (Bev). PATIENTS AND METHODS Forty-nine patients with unresectable colorectal liver metastases (CRLM) were included in a single-institution phase II trial. Conversion to resection was the primary outcome...

BACKGROUND Energy efficiency analysis for different biomass-utilization scenarios would help make more informed decisions for developing future biomass-based transportation systems. Diverse biofuels produced from biomass include cellulosic ethanol, butanol, fatty acid ethyl esters, methane, hydrogen, methanol, dimethyether, Fischer-Tropsch diesel, and bioelectricity; the respective powertrain s...

521 Background: Bevacizumab (BEV) addition to doublet chemotherapy significantly increases efficacy without differentially affecting prognosis in KRAS wild-type (wt) and mutant (m) MCRC. Present study evaluates clinical outcome of BEV added to triplet chemotherapy, FIr-B/FOx (Bruera G et al, BMC Cancer 2010, 10:567), according to KRAS genotype. METHODS MCRC patients (pts) were treated with fi...