In this review, we have discussed efficacy of percutaneous biliary drainage not only in cases with malignant bi l iary obstructive jaundice, but accompanying bilomas as well. Percutaneous biliary drainage is mostly successful. Direct bilirubin levels can be decreased significantly as in our previous series, which has a success of 89.5% of malignant biliary drainages and all associated bilomas. ...

Many different benign and malignant diseases can cause extrahepatic biliary duct obstruction. Common causes include calculus of the bile duct, stenosis, and tumors. Bile duct obstruction is often complicated bybacterial infection due to acute cholangitis, leading toan increase in the bile duct pressure and entry ofa large number of bacteria and toxins into the blood circulation. Consequently, a...

SEVERE, rapidly progressive, obstructive jaundice is probably most frequently due to neoplastic obstruction of the biliary tract either within the hepatic substance or in its extra-hepatic part. The obstruction when complete produces profound metabolic changes which are on the whole poorly understood and these changes are reflected in changes in the blood chemistry. In the differential diagnosi...

Hypocholesteremia with dissociation of the normal ratio of esterified to total cholesterol is related to chronic liver injury caused by chloroform. Hypercholesteremia may develop after prolonged biliary obstruction. The hypercholesteremia of chronic biliary obstruction may be promptly reduced below normal by chloroform poisoning or bile duct infection. Acute injury of liver due to chloroform an...

BACKGROUND Malignant biliary obstruction is often inoperable at presentation and has a poor prognosis. Percutaneously placed self-expanding metal stents (SEMS) have been widely used for palliation of malignant biliary obstruction as an alternative to major bypass surgery or when endoscopic drainage is not technically feasible. The success rate, procedural complications and outcomes in patients ...

Gallbladder stones are an extremely common disorder and are usually asymptomatic, but they may cause insidious infections. Acute cholecystitis is a bacterial infection caused by an obstruction of the cystic duct with gallstones. The obstruction results in gallbladder distention, wall edema, ischemia and bacteria infection. The wall of the gallbladder may undergo necrosis and gangrene and ultima...

The exact cause of liver failure occurring after long standing biliary obstruction is not known. Impairment of hepatic mitochondrial respiration was postulated in some studies. Sodium thiosulphate (STS) is known to have a protective effect on liver function during administration of hepatotoxic chemotherapy. In the present experimental study the effect of treatment with STS in the presence of ob...