BACKGROUND Lepidium meyenii Walpers (maca) is an herb known as a traditional nutritional supplement and widely used in Peru, North America, and Europe to enhance human fertility and treat osteoporosis. The secondary metabolites of maca, namely, maca alkaloids, macaenes, and macamides, are bioactive compounds, but their targets are undefined. METHODS The pharmacophore-based PharmaDB targets da...

Indonesia, especially in the Riau Islands has abundant marine biological natural resources. So that it can be used as basic ingredient of a search for medicinal or materials. One them is caulerpa racemosa sea grape type from green algae group which contains variety secondary metabolites with bioactive compounds are cytotoxic to kill cancer cells. This study aims determine activity ethanol extra...

background & aim:combretaceae family is   known for efficacy in the management of sickle cell disorder (scd). based on   the earlier reports of anti-sickling property of terminalia genus the study investigates in vitro antisickling properties of terminalia arjuna and terminalia   bellirica. experimental: anti-sickling   assay of methanolic and aqueous extract of t. arjuna and t. bellirica   on ...

BACKGROUND Ergot alkaloids are a group of highly bioactive molecules produced by a number of filamentous fungi. These compounds have been intensely studied for decades, mainly due to their deleterious effects in contaminated food and feeds, but also for their beneficial pharmaceutical and agricultural applications. Biosynthesis of ergot alkaloids goes via the common intermediate chanoclavine-I,...

Seaweed is a biological resource that rich in nutrients and bioactive compounds. This study aims to determine qualitatively quantitatively the compounds (flavonoids, alkaloids, steroids/terpenoids, saponins phenols) from extracts fractions of Eucheuma cottonii. The method used an experiment by conducting series experiments extracting fractionating E. cottonii data were analyzed descriptively. t...

background & aim: papaver bracteatum lindl.  (papaverace) is an important pharmaceutical plant which contains isoqinoline alkaloids. isoqinoline alkaloids constitute one distinct group of secondary metabolites of the papaverace family. codeine and thebaine are important alkaloids of papaver bracteatum which use widely due to its medicinal properties. therefore it is necessary to determinati...

objective(s): evaluation of the sophora alopecuroides var. alopecuroides seed effects on morphine withdrawal syndrome in mice and determination of the alkaloid composition of the seed total extract. materials and methods:the effects of the seed total extract, alkaloid fraction and major compound matrine on the mice morphine withdrawal syndrome were compared to saline and methadone.mice were mad...

Lupines (Lupinus spp.) have emerged as a cheap functional food with the advantages of being non-genetically modified crop, able to adapt harsh conditions and low-input farming. are rich in protein poor starch, similar soy. The factor limiting use lupine is presence quinolizidine alkaloids especially bitter species. Nevertheless, modern breeding programs ensured selection sweet species reduced a...

The phytochemicals present in medicinal plants are effective and safe alternative to the chemically synthesized drugs for various diseases. Madagascar periwinkle grown as ornamental plant its flowers. It is an evergreen that was native Island. so special due variety of bioactive compounds which have values, including anti-inflammatory, anti-cancer anti-diabetic quality. This study aims investig...