In Italy, Ecotoxicology has found a place with the Legislative Decree n. 152 (May 11, 1999), emanated in fulfilment of the Directives 91/271/CEE "urban waste-water treatment" and 91/676/CEE "protection of waters against pollution caused by nitrates from agricultural sources". This decree in reality goes beyond (actually anticipating the content of the Framework Directive on Water, still under w...

Peripheral proteins transiently interact with cellular membranes where they regulate important cellular events such as signal transduction. A number of peripheral proteins harbor lipid-binding modules that not only bind selectively with nanomolar affinity to biological membranes but also oligomerize on the membrane surface. In some cases, specific lipid binding or specific lipid compositions ca...

BACKGROUND Biological monitoring (BM) aids exposure assessment but where this is based on incomplete collections of single urine voiding measurement of creatinine is often used to adjust analyte concentrations for the effects of fluid balance. AIMS To provide reference data on creatinine concentrations in urine samples from a population of UK workers. METHODS Urine samples sent to the Healt...

Blood tests are necessary, easy-to-perform and low-cost alternatives for monitoring of oncolytic virotherapy and other biological therapies in translational research. Here we assessed three candidate proteins with the potential to be used as biomarkers in biological fluids: two glucuronidases from E. coli (GusA) and Staphylococcus sp. RLH1 (GusPlus), and the luciferase from Gaussia princeps (GL...

Biological invasions of freshwater habitats are due to the accidental or deliberate introduction of organisms associated to aquaculture, sports fishing, passive transport by vessels, ornamental uses and man-made canals and corridors. In European freshwater habitats, about 296 species of alien invertebrate, mostly crustaceans, and 136 species of alien fish have been introduced (Gherardi et al. 2...

The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory bio...

Exposure of health care workers to antineoplastic drugs and subsequent adverse health effects is still an open issue. Very little has been studied on the extent of occupational exposure and handling conditions of antineoplastic drugs in Iran. We aimed to determine cyclophosphamide and ifosfamide concentrations in the urine samples of oncology healthcare workers. In addition, we assessed workpla...

Background: This study has used biomarker of exposure-effect continuum to examine the biological characteristics of organophosphate (OP) toxicity and its genotoxic effect among rice farmers. Materials and Methods: A cross-sectional study was conducted among 160 pesticide exposed rice farmers and 160 adults from the fishing village as the unexposed group. They share the common socio-economical ...