The development of technology for use in resource-poor countries encounters a specific type of challenge not ordinarily faced in academic science: the technology must be inexpensive and it must work with minimal infrastructure. This challenge is particularly severe when the problems being solved are, by their nature, ones that require high-technology solutions. For these kinds of problems, the ...

The development of vaccines for microorganisms and bacterial toxins with the potential to be used as biowarfare and bioterrorism agents is an important component of the US biodefense program. DVC is developing two vaccines, one against inhalational exposure to botulinum neurotoxins A1 and B1 and a second for Yersinia pestis, with the ultimate goal of licensure by the FDA under the Animal Rule. ...

Smallpox (variola major), and the haemorrhagic fever viruses (filoviruses and arenaviruses) are classified as Category A biowarfare agents by the Centers for Disease Control. Category A agents pose a significant risk to public health and national security because they can be easily disseminated by aerosol, although with the exception of variola, they are not easily transmitted from person to pe...