The renormalization group, a powerful method that uses the tools of quantum field theory, has found place in biophysics.

Biomechanics may be considered a branch of biophysics that involves the application mechanical principles to better our understanding structure, function, and motion living organisms [...]

ABSTRACT Biophysics is an interdisciplinary pursuit requiring researchers with knowledge and skills in several areas. Optical instruments computers are fundamental tools biophysics research to collect analyze data. We developed a 1-semester Engineering Laboratory course teach image processing, optical engineering, undergraduate students majoring biology biochemistry. With the use of development...

While digitizing the human genome has been one of the major recent scientific achievements, unraveling genome structure and, more importantly, structure/function relationships has been a major preoccupation for many scientific teams worldwide. Indeed, the understanding of structure from the DNA level to nucleosomes, chromatin fibers, genes, and chromosomes holds the key to interpreting many of ...

Biophysics at the systems level, as distinct from molecular biophysics, acquired its most famous paradigm in the work of Hodgkin and Huxley, who integrated their equations for the nerve impulse in 1952. Their approach has since been extended to other organs of the body, notably including the heart. The modern field of computational biology has expanded rapidly during the first decade of the twe...

EDITORIAL article Front. Phys., 09 March 2023Sec. Biophysics Volume 11 - 2023 | https://doi.org/10.3389/fphy.2023.1177418

In this study, we explore nucleation and the transition state ensemble of the ribosomal protein S6 using a Monte Carlo Go model in conjunction with restraints from experiment. The results are analyzed in the context of extensive experimental and evolutionary data. The roles of individual residues in the folding nucleus are identified and the order of events in the S6 folding mechanism is explor...

Whole human genome sequencing of individuals is becoming rapid and inexpensive, enabling new strategies for using personal genome information to help diagnose, treat, and even prevent human disorders for which genetic variations are causative or are known to be risk factors. Many of the exploding number of newly discovered genetic variations alter the structure, function, dynamics, stability, a...

Why were Hodgkin and Huxley so disappointed with their work? Through a brilliant train of thought that considered the linearity of the current-voltage curve and the relative amplitudes of ionic and gating currents (Hodgkin and Huxley, 1952), they concluded that the Na 1 current which drives the action potential passes through a channel—defined as a pore that passes ions at high rates compared t...