Functional kinked nanowires (KNWs) represent a new class of nanowire building blocks, in which functional devices, for example, nanoscale field-effect transistors (nanoFETs), are encoded in geometrically controlled nanowire superstructures during synthesis. The bottom-up control of both structure and function of KNWs enables construction of spatially isolated point-like nanoelectronic probes th...

An innovative approach for up-converting nanoparticles adaptation for bio-related and theranostic applications is presented. We have successfully encapsulated multiple, ~8 nm in size NaYF4 nanoparticles inside the polymeric nanocarriers with average size of ~150 nm. The initial coating of nanoparticles surfaces was preserved due to the hydrophobic environment inside the nanocapsules, and thus n...

Fluorescent labeling techniques have been widely used in live cell studies; however, the labeling processes can be laborious and challenging for use in non-transfectable cells, and labels can interfere with protein functions. While label-free biosensors have been realized by nanofabrication, a method to track intracellular protein dynamics in real-time, in situ and in living cells has not been ...

We report a dual functional aggregation-enhanced emission (AEE) molecule, TPE-IQ, which could target and illuminate mitochondria in both live and fixed cells with superb selectivity and high signal-to-noise ratio. More intriguingly, TPE-IQ can serve as a photosensitizer to generate reactive oxygen species (ROS) in the mitochondria region to induce cell apoptosis.

Overexpression of epidermal growth factor receptor (EGFR) has been implicated in tumor development and malignancy. Evaluating the degree of EGFR expression in tumors could aid in identifying patients for EGFR-targeted therapies and in monitoring treatment. Nevertheless, no currently available assay can reliably quantify receptor content in tumors. Radiolabeled inhibitors of EGFR-TK could be dev...

BACKGROUND While hepatitis E virus (HEV) mostly causes self-limited disease in general population, it is more severe in pregnant women. OBJECTIVES This study aimed to investigate the seroprevalence of anti-HEV IgG among a population of pregnant women in West Azerbaijan of Iran . PATIENTS AND METHODS One hundred thirty six pregnant women referred to urban health centers of Urmia for pursuing...

Due to their hydrophilic, biocompatible, and highly tunable nature, hydrogel materials have attracted strong interest in the recent years for numerous biotechnological applications. In particular, their solution-like environment and non-fouling nature in complex biological samples render hydrogels as ideal substrates for biosensing applications. Hydrogel coatings, and later, gel dot surface mic...

Antibiotics are widely used to kill or inhibit microorganisms, but their abuse results in various types of side effects in humans and the appearance of super bacteria with tolerance to antibiotics. Excess residual antibiotics in food products have become a serious problem, and so a more reliable, accurate, and easier detection system has been required. Aptamers have strong potential as sensitiv...

The past decade has witnessed an explosion of interest in the development of luminescent nanoparticles because of their excellent potentials in biomedical application. Most recently, lanthanide ion (Ln) doped upconversion nanoparticles (UCNPs), typically NaMF4:Yb /Ln (M= yttrium or gadolinium, Ln= erbium or thulium), have become an exciting new class of nanophosphors that convert nearinfrared (...