OBJECTIVE To compare the prevalence rates of mental disorders among children of parents with bipolar disorder and of parents with no mental disorders. METHOD Seventeen studies, meeting specific selection criteria, were included in the metaanalyses. Risks for mental disorders among children were estimated by aggregating raw data from the selected studies. RESULTS Results indicate that in com...

Background: Iran is facing an outbreak of methamphetamine-induced disorders and frequent use of these substances in patients with bipolar disorder. Using or intoxication of methamphetamine in patients with bipolar I disorder may alter the patient's clinical profile; however there is limited studies about impact of methamphetamine on clinical manifestation of bipolar disorders. This study aimed ...

Bipolar disorders are common, disabling, recurrent mental health conditions of variable severity. Onset is often in late childhood or early adolescence. Patients with bipolar disorders have higher rates of other mental health disorders and general medical conditions. Early recognition and treatment of bipolar disorders improve outcomes. Treatment of mood episodes depends on the presenting phase...

purpose: bipolar disorders of complex and multi-dimensional nature necessitate new therapies.   this research compared the effect of meta-cognitive and psycho-educational family therapy on   dysfunctional attitudes of bipolar patients.   materials and methods: this was a semi-empirical research with pretest-posttest design, using   control group. from among the bipolar woman who had referred to...

Given its prevalence and impact on public health, the comorbidity of bipolar and substance use disorders is one of the most relevant of dual diagnoses. The objective was to evaluate the characteristics of patients from community mental health and substance abuse centres in Madrid. The sample consisted of 837 outpatients from mental health and substance abuse centres. We used the Mini Internatio...

OBJECTIVE The purpose of this study was to test whether borderline personality disorder is a variant of bipolar disorder by examining the rates of co-occurrence in both disorders, the effects of co-occurrence on a longitudinal course, and whether the presence of either disorder confers the risk for new onsets of the other. METHOD A prospective repeated-measures design with reliable independen...

OBJECTIVE Bipolar spectrum disorders may often go undiagnosed or unrecognized. The aim of this study was to determine the proportion of bipolar disorder symptoms in Iranian patients with a major depressive episode. METHODS 313 patients with a current DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders 4th ed. Text rev.) diagnosed with a major depressive episode entered this cross...

Progress in the treatment of bipolar disorder Bipolar affective disorder has long been recognized as being one of the most significant causes of increased mortality and morbidity due to mental ill health. Bipolar disorder is an evolution of the older concept of manic-depressive illness, which itself was differentiated from dementia praecox/schizophrenia by Kraepelin over 100 years ago. Bipolar ...

Key Study Findings The authors report a multicenter (N = 497), randomized, double-blind, placebo-controlled study (NCT01058668). Patients were randomly assigned to placebo, cariprazine 3–6 mg/d, or cariprazine 6–12 mg/d for 3 weeks. The primary outcome was change from baseline to week 3 utilizing the Young Mania Rating Scale (YMRS). Both cariprazine groups were statistically significantly super...