The synthesis and cation-binding properties of a series of Calixarene derivatives possessing alkyl chain groups, ester groups and crown ether rings have been investigated. The syntheses of Calix[4]arene crown ethers and Calix[6]arene derivatives possessing alkyl chain, ester group and crown ether ring have been described. In order to evaluate their monovalent cation binding abilities, solvent e...

METHYL N-PIqOPYL ETHER was first described by Chancel in 1869, but its valuable anaesthetm properties were not apprecmted unlal its inclusion in the long senes of ethers tested by Krantz and has co-workers m the United States. The clinical trials of methyl n-propyl ether fol/owing Krantz's original description of its anaesthetic properties and pharmacology m 1946 (1) showed that it might be sup...

Ether Lipid Metabolism Ether-linked glycerolipids are present in most mammalian tissues including brain, kidney, heart and skin. They were once strictly referred to as structural components of membranes, but by now it is known that some are biologically active (1). Ether lipids have as important roles as maintaining proper brain function, spermatogenesis, mediation of inflammation and lens orga...

1-Alkyl-sn-glycero-3-phosphate:acyl-CoA acyltransferase activity was found in six rat tissues: heart, spleen, brain, kidney, liver, and lung. The enzyme in rat brain showed highest specific activity in the microsomal fraction and its properties were studied in detail. Triton X-100 and bovine serum albumin were found to stimulate the activity of the enzyme. It was found that Triton X-100 affects...

The photooxidation of diethyl ether (C2H5OC2H5) and diisopropyl ether, (CH3)2CHOCH(CH3)2, in the presence of NOx was studied at the European Photoreactor (EUPHORE) in May 1998. The main objective of the experiments was to validate the degradation mechanisms that are based on data obtained from laboratory photoreactor studies. For diisopropyl ether, the experiments provided product yield data th...

Two supramolecular coordination polymers, [HgI2(L )·0.5H2O]∞ (1) and [HgI2(L )·0.4CH3OH]∞ (2), have been prepared by ligands L 1 (L = bis[4-(4pyridylmethyleneamino)phenyl] ether) and L (L = N,N′-bis(3-pyridylmethyl)-diphthalic diimide) with HgI2, respectively. 1 formed an interestingly infinite cross-linked double helical structure, whereas 2 formed the one-dimensional zigzag chains, which are ...

A chiral phosphoric acid-catalyzed intramolecular 1,3-dipolar cycloaddition of 4-(2-formylphenoxy)butenoates with amino esters provides hexahydromeno[4,3-b]pyrrolidine derivatives in high enantioselectivity (up to 94% ee).

The glycerolipids of most cells are characterized by a specific proportion of ether linkages at the sn-1 position of the glycerol backbone. A number of tumors are known to have altered concentrations of ether-linked lipids compared to normal tissues. However, no through examination of the ether-lipid content of human leukemia cells has been reported despite the importance of these lipids in nor...

The synthesis of new pinene-derived chiral cyclopropylamines and their use in the synthesis of the first asymmetric Alkyl-BIAN ligands (Alkyl-BIAN = bis-(alkylimino)acenaphthenequinone) are reported.

Previous studies have shown that the human lens contains glycerophospholipids with ether linkages. These lipids differ from conventional glycerophospholipids in that the sn-1 substituent is attached to the glycerol backbone via an 1-O-alkyl or an 1-O-alk-1'-enyl ether rather than an ester bond. The present investigation employed a combination of collision-induced dissociation (CID) and ozone-in...