A novel immobilized dehydrocondensing reagent comprised of a triazine-type dehydrocondensing reagent itself in a polymerized form was synthesized by copolymerization between tetra(ethylene glycol) bis(dichlorotriazinyl) ether and tris(2-aminoethyl)amine.

We report a catalytic asymmetric total synthesis of the ascidian natural product perophoramidine. The synthesis employs a molybdenum-catalyzed asymmetric allylic alkylation of an oxindole nucleophile and a monosubstituted allylic electrophile as a key asymmetric step. The enantioenriched oxindole product from this transformation contains vicinal quaternary and tertiary stereocenters, and is obt...

Time-dependent ovulation-blocking effect of ether anesthesia was investigated using female Wistar-Imamichi rats showing a 4-day cycling rhythm. A 6-hr (1400-2000) and 8-hr (1400-2200) anesthesia with ether vapor on proestrus caused ovulation blockade in 85% and 100% of the rats, respectively. On the other hand, pentobarbital injections at 1400 and 1500 completely blocked the spontaneous ovulati...

A halogen-induced oxidative rearrangement of N,O-ketals prepared from cyclobutanones, leading to pyrrolidone derivatives, is developed. The reaction proceeds via an iminium ether intermediate and, depending on the reaction medium, two types of pyrrolidone derivative, containing a halogen atom or hydroxyl group, can be obtained.

The reaction of bis(pentafluorophenyl)mercury with the ligands bis(diphenylphosphano) methane P,P’-dioxide ({Ph2P(O)}2CH2) (1), bis{2-(N,N,N’N’-tetraethyldiaminophosphano) imidazol-1-yl} ({2-PO(NEt2)2C3N2H2}2CH2) (2) and bis (2-diphenylphosphanophenyl) ether ({2-PPh2(O)C6H4}2O) (3) afforded crystalline σ-donor complexes [{Hg(C6F5)2}2{Ph2P(O)}2CH2] (1Hg), [Hg(C6F5)2{2-PO(NEt2)2C3N2H2}2CH2]n (2Hg...

The donor-free trimethylsilylmethyllithium [LiCH(2)SiMe(3)](6) hexameric aggregate is for the first time broken up by simple ether donors such as diethyl ether (Et(2)O) and tert-butylmethyl ether ((t)BuOMe) to give the unprecedented asymmetric tetramers while the chelating dimethoxyethane (DME) gives the expected dimer.

Abstract—Five palm oil ether monoesters utilized as novel biodiesels were synthesized and structurally identified in the paper. The investigation was made on the effect of ether species on physicochemical properties of the palm oil ether monoesters. The results showed that density, kinematic viscosity, smoke point, and solidifying point increase linearly with their –CH2 group number in certain ...

The purpose of this study was to define the dual effects of saturable metabolism and saturable protein binding on the pharmacokinetics of diflunisal. Steady-state diflunisal concentration and its unbound fraction were examined in seven groups of rats to determine the relationships of infusion rate, concentration and total and unbound clearances. The total body plasma clearance decreased initial...