Chronic myeloid leukemia (CML) is a disease of the hematopoietic system, characterized by the presence of the Bcr-Abl oncoprotein. The main characteristics of this disease include adhesion independence, growth factor independence, and resistance to apoptosis. Loss or mutation of the tumor suppressor gene, p53, is one of the most frequent secondary mutations in CML blast crisis. The transition b...

Abstract One of the biotic constraints in rice production worldwide is blast disease which can control by planting resistant varieties. To find out effective resistance, resistance quantitative trait loci (QTL) were mapped against 20 and 3 virulent isolates for leaf neck blast, respectively, using 111 doubled haploid lines from cross IR64 Azucena. QTLs associated with found on chromosomes 1, 2,...

Rice is a staple food source for more than three billion people worldwide. However, rice is vulnerable to diseases, the most destructive among them being rice blast, which is caused by the fungus Magnaporthe oryzae (anamorph Pyricularia oryzae). This fungus attacks rice plants at all stages of development, causing annual losses of approximately 10-30% in various rice producing regions. Syntheti...

Chronic myeloid leukemia(CML) usually remains asymptomatic and has varied clinical presentation. The disease usually has a chronic course till it goes into blast crisis when it develops fever, other constitutional symptoms and bleeding manifestations as seen in acute leukemia. Here, we present a case that came to our emergency department as a case of acute abdomen in the form of massive retrope...

The Pyricularia genus includes several pathogenic fungi species that are associated with blast disease in more than 50 Poaceae plants (Ou 1985). Among these species, Pyricularia oryzae is the most important pathogen, due to its global distribution on plants from the Poaceae family. The blast disease caused by P. oryzae is responsible for severe losses in crops of high economic importance such a...

Background: Aberrant expression of cross-lineage antigens gives valuable insight into the diagnosis and prognosis of acute leukemia. In countries like India, cytogenetic tests are widely accessible. Exploring the prognostic value of an accessible test is of great importance. Therefore, establishing a population-specific immunophenotype database will enable to design an antibody panel equipped t...

BACKGROUND The coupling of biotic and abiotic stresses leads to high yield losses in rainfed rice (Oryza sativa L.) growing areas. While several studies target these stresses independently, breeding strategies to combat multiple stresses seldom exist. This study reports an integrated strategy that combines QTL mapping and phenotypic selection to develop rice lines with high grain yield (GY) und...

In a case of acute leukemia occurring 5.5 yr after diagnosis of Hodgkin's disease, a mixture of lymphoid and myelomonocytoid blasts was identified by morphological, cytochemical, and immunologic methods. The majority of blasts were characterised as lymphoid by their strong expression of nuclear terminal transferase (TdT) enzyme. In contrast, a minor blast population was identified as myelomonoc...

Synthetic studies on bioactive compounds are described, involving phytotoxins (tobacco wildfire disease toxin tabtoxinine-beta-lactam and rice blast disease toxin pyricuol) a glutarimide antibiotic (actiketal) black vomit toxin (gizzerosine) and marine products (antifeedant pteroenone and serinol compound didemniserinolipid).

ABSTRAKPenyakit leaf blast disebabkan oleh jamur yang bernama Pyricularia Grisea dapat menginfeksi daun padi dan menyebabkan gejala penyakit seperti bercak berbentuk belah ketupat berwarna coklat mengakibatkan kematian pada tanaman. Tingkat penyebaran sudah meluas hingga di Indonesia yakni sentra-sentra produksi padi. Penelitian dilakukan untuk mengidentifikasi Daun Padi dengan ekstraksi ciri G...