BackgroundHeavy menstrual bleeding affects the physical functioning and social well-being of many women. The levonorgestrel-releasing intrauterine system endometrial ablation are 2 frequently applied treatments in women with heavy bleeding.ObjectiveThis study aimed to compare effectiveness bleeding.Study DesignThis multicenter, randomized controlled, noninferiority trial was performed 26 hospit...

BACKGROUND Treatment with vitamin K antagonists (coumarins) is associated with an increased risk of bleeding. Because use of selective serotonin reuptake inhibitors (SSRIs) is also associated with an increased risk of bleeding, we assessed the odds ratio (OR) of abnormal bleeding associated with SSRI use in users of the coumarins acenocoumarol or phenprocoumon and compared this with the OR of b...

In a previous publication on new terminology, definitions, and outcome criteria for immune thrombocytopenia (ITP), the International Working Group (IWG) on ITP acknowledged that response to treatment should consist of clinically meaningful end points such as bleeding manifestations and that platelet count may not be the ideal parameter for capturing the benefits of therapy. The IWG now proposes...

background : rectal bleeding is a relatively uncommon, but potentially important problem in early infancy.  the common causes of fresh rectal bleeding in this age group are: bleeding diathesis (vit. k deficiency), infectious colitis, cow’s milk protein allergy and anal fissure.  nodular lymphoid hyperplasia (nlh) is another cause of prolonged fresh rectal bleeding in early infancy.   objective:...